Using Hydroxychloroquine to Treat Nonalcoholic Steatohepatitis
NCT05733897 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2023-03-02
Summary
Nonalcoholic steatohepatitis (NASH) is a serious type of nonalcoholic fatty liver disease (NAFLD), which is characterized by lobular inflammation and apoptosis resulting from hepatic steatosis in the absence of excessive alcohol consumption. If NASH are not controlled well, it will advance to liver fibrosis, cirrhosis, and even hepatocellular carcinoma. However, there is no approved treatments currently.
The investigators aim to clarify whether hydroxychloroquine relieves nonalcoholic steatohepatitis by reviewing medical records from our out-patient-clinic patients who accept the treatment of hydroxychloroquine (Plaquenil®).
Conditions
Interventions
- DRUG
-
hydroxychloroquine
Using hydroxychloroquine to treat nonalcoholic steatohepatitis
Sponsors & Collaborators
-
National Taiwan University
collaborator OTHER -
National Taiwan University Hospital
lead OTHER
Principal Investigators
-
Chung-Jui Huang, Master · Graduate Institute of Pharmacology, College of Medicine, National Taiwan University
-
Feng-Chiao Tsai, Doctor · Graduate Institute of Pharmacology, College of Medicine, National Taiwan University
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-06-10
- Primary Completion
- 2025-07-01
- Completion
- 2025-07-01
Countries
- Taiwan
Study Locations
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