Netherlands Cohort Study on Acute HIV Infection
NCT05728996 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 183
Last updated 2023-02-15
Summary
Investigation of the size, variability and localization of the (pro) viral reservoir and the properties of HIV-specific immune response related to "post-treatment viral remission' achievement and / or duration. In addition we will study the factors that determine latency in the different host cells, their sensitivity to induction of replication competent virus by various agents and the potential application of these agents in "post-treatment viral remission".
This all will be studied in patients included during acute phase of the infection who start antiretroviral therapy immediately upon diagnosis.
Conditions
- Acute HIV Infection
Sponsors & Collaborators
-
UMC Utrecht
collaborator OTHER -
Rijnstate Hospital
collaborator OTHER - collaborator OTHER
-
Onze Lieve Vrouwe Gasthuis
collaborator OTHER -
Radboud University Medical Center
collaborator OTHER -
Maasstad Hospital
collaborator OTHER -
DC Clinics
collaborator UNKNOWN -
Amsterdam UMC, location VUmc
collaborator OTHER -
Leiden University Medical Center
collaborator OTHER -
Prof. Jan Prins
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-08-01
- Primary Completion
- 2028-08-01
- Completion
- 2028-08-01
Countries
- Netherlands
Study Locations
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