Netherlands Cohort Study on Acute HIV Infection

NCT05728996 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 183

Last updated 2023-02-15

No results posted yet for this study

Summary

Investigation of the size, variability and localization of the (pro) viral reservoir and the properties of HIV-specific immune response related to "post-treatment viral remission' achievement and / or duration. In addition we will study the factors that determine latency in the different host cells, their sensitivity to induction of replication competent virus by various agents and the potential application of these agents in "post-treatment viral remission".

This all will be studied in patients included during acute phase of the infection who start antiretroviral therapy immediately upon diagnosis.

Conditions

  • Acute HIV Infection

Sponsors & Collaborators

  • UMC Utrecht

    collaborator OTHER
  • Rijnstate Hospital

    collaborator OTHER
  • Erasmus Medical Center

    collaborator OTHER
  • Onze Lieve Vrouwe Gasthuis

    collaborator OTHER
  • Radboud University Medical Center

    collaborator OTHER
  • Maasstad Hospital

    collaborator OTHER
  • DC Clinics

    collaborator UNKNOWN
  • Amsterdam UMC, location VUmc

    collaborator OTHER
  • Leiden University Medical Center

    collaborator OTHER
  • Prof. Jan Prins

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-08-01
Primary Completion
2028-08-01
Completion
2028-08-01

Countries

  • Netherlands

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05728996 on ClinicalTrials.gov