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Dynamic Changes of Torquetenovirus (TTV) Load in Chinese Renal Transplant Recipients

NCT05727709 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 220

Last updated 2023-08-22

No results posted yet for this study

Summary

The goal of this observational study is to learn about dynamic changes of Torquetenovirus (TTV) load in Chinese renal transplant recipients. The main questions it aims to answer are:

* Is there correlation between TTV load and rejection?
* Is there correlation between TTV load and infection?
* Can changes in the TTV load of kidney transplant recipients predict rejection or infection?

Participants will:

* receive 13 follow-up visits within 1 year after kidney transplantation
* provide 2 ml of whole blood for TTV load testing and other related testing at each follow-up
* provide 10 ml of whole blood for dd-cfDNA testing at four follow-ups (1, 3, 6 and 12 months after transplantation)
* provide 1 ml of serum for donor-specific antibody testing at three follow-ups (1, 6 and 12 months after transplantation)

Conditions

  • Kidney Transplant Rejection
  • Kidney Transplant Infection
  • Virus
  • Immunosuppression

Sponsors & Collaborators

  • Anapure BioScience

    collaborator UNKNOWN

  • Caibo MedTech

    collaborator UNKNOWN

  • SKM BioTech

    collaborator UNKNOWN

  • Tongji Hospital

    lead OTHER

Principal Investigators

  • Gang Chen, PhD · Tongji Hospital

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-03-15
Primary Completion
2023-12-31
Completion
2024-06-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05727709 on ClinicalTrials.gov