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Analysis of Muscular Properties in Patients With MFS and EDS

NCT05720923 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 65

Last updated 2025-09-10

No results posted yet for this study

Summary

The goal of this observational study is to learn and assess muscle morphological and electromechanical properties in patients affected with Marfan syndrome (MFS) and Ehlers Danlos syndrome (EDS). the main questions it aims to answer are:

* To assess the ability to develop muscle strength;
* Muscle and tendon morphology involved in muscle contractions/relaxation;
* Neuromuscular functionality.

Participants will be take part in the study by performing a test for the assessment of the neuromuscular activity (voluntary muscle contractions) and undergoing a muscle ultrasound for the study of muscles and tendons.

Researchers will compare the two groups with a control group to see potential differences in the morphological and neuromuscular structures of syndromic patients.

Conditions

Interventions

DEVICE

Analysis with Ergometer

The analysis with the ergometer aims at assessing neuromuscular function

Sponsors & Collaborators

  • University of Milan

    collaborator OTHER

  • IRCCS Policlinico S. Donato

    lead OTHER

Principal Investigators

  • Giuliana Trifirò, MD · IRCCS Policlinico S. Donato

Eligibility

Min Age
12 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-02-15
Primary Completion
2025-07-30
Completion
2026-01-31

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05720923 on ClinicalTrials.gov