Open-Label Extension of Tocilizumab in Subjects With Generalized Myasthenia Gravis
NCT05716035 · Status: RECRUITING · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 64
Last updated 2024-01-22
Summary
To evaluate the safety and efficacy of tocilizumab in the treatment of generalized myasthenia gravis (gMG) as an extension study for the participants who previously completed Study tMG(NCT05067348).
Conditions
- Myasthenia Gravis, Generalized
Interventions
- DRUG
-
Tocilizumab Injection
Participants will receive IV tocilizumab
Sponsors & Collaborators
-
Tang-Du Hospital
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-04-01
- Primary Completion
- 2024-07-31
- Completion
- 2024-12-31
Countries
- China
Study Locations
More Related Trials
-
Safety,Tolerability,Pharmacokinetics and Efficacy of CFZ533 in Moderate to Severe Myasthenia Gravis
NCT02565576 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Low-dose Rituximab in the Treatment of Refractory Myasthenia Gravis
NCT05332587 ·Status: UNKNOWN ·Phase: PHASE3
-
GC012F Injection in the Treatment of Refractory Generalized Myasthenia Gravis(24103)
NCT07058298 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
An Open Study for Steroid Resistant, Non-Thymectomized MG Patients
NCT00309101 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis
NCT07039916 ·Status: RECRUITING ·Phase: PHASE3
-
An Extension Study of MOM-M281-004 to Evaluate the Safety, Tolerability, and Efficacy of M281 Administered to Patients With Generalized Myasthenia Gravis
NCT03896295 ·Status: TERMINATED ·Phase: PHASE2
-
A Study in Patients With Myasthenia Gravis in China
NCT06700616 ·Status: ACTIVE_NOT_RECRUITING
-
Study to Test the Safety, Tolerability and Efficacy of UCB7665 in Subjects With Moderate to Severe Myasthenia Gravis
NCT03052751 ·Status: COMPLETED ·Phase: PHASE2
-
A Prospective Cohort Study of Myasthenia Gravis in China
NCT06006832 ·Status: RECRUITING
-
An Exploratory Clinical Study of GC012F Injection for Refractory gMG
NCT06419166 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Eculizumab in Chinese Adults With gMG
NCT06764160 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis
NCT06704269 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Clinical Prognosis and Progression of Myasthenia Gravis Patients
NCT04101578 ·Status: UNKNOWN
-
FK506 Phase 3 Study: a Study for Steroid Non-resistant Myasthenia Gravis (MG) Patients
NCT00309088 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis
NCT06744920 ·Status: RECRUITING ·Phase: PHASE3
-
A Clinical Study of B007 in the Treatment of Generalized Myasthenia Gravis.
NCT06447597 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
A Study to Evaluate the Safety and Preliminary Efficacy of SYS6020 CAR T-cells in Patients With Refractory Generalized Myasthenia Gravis
NCT06688435 ·Status: RECRUITING ·Phase: PHASE1
-
A Study to Compare the Efficacy and Safety of Tacrolimus Capsules in Patient With Myasthenia Gravis
NCT01325571 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis
NCT06106672 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Telitacicept and Low-dose Steroids in Refractory Myasthenia Gravis
NCT06723548 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Disease-Modifying Treatments for Myasthenia Gravis
NCT03490539 ·Status: COMPLETED
-
TheRapeutic Effect of Different immunosuppressAnts on Non-Thymoma Ocular Myasthenia Gravis: a Real-world Study
NCT04182984 ·Status: RECRUITING
-
A Phase 3, Open-label, Crossover Study to Evaluate Self-administration of Rozanolixizumab by Study Participants With Generalized Myasthenia Gravis (gMG)
NCT05681715 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of M281 Administered to Adults With Generalized Myasthenia Gravis
NCT03772587 ·Status: COMPLETED ·Phase: PHASE2
-
Safety And Efficacy Of Tofacitinib In Patients With Refractory Myasthenia Gravis: A Pilot Study
NCT04431895 ·Status: COMPLETED ·Phase: EARLY_PHASE1