Neoadjuvant Platform Trial in Non-Small Cell Lung Cancer
NCT05714891 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 4
Last updated 2026-02-12
Summary
This study is being done to answer the following question: What are the effects of new treatments on non-small cell lung cancer before surgery?
Conditions
Interventions
- DRUG
-
JDQ443
Dose will be assigned at enrollment
Sponsors & Collaborators
- collaborator INDUSTRY
-
Canadian Cancer Trials Group
lead NETWORK
Principal Investigators
-
Jonathan Spicer · McGill University, Montreal, QC Canada
-
Normand Blais · CHUM-Centre Hospitalier de l'Universite de Montreal, QC Canada
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-09-15
- Primary Completion
- 2026-08-31
- Completion
- 2028-03-31
Countries
- Canada
Study Locations
More Related Trials
-
Neoadjuvant Immunotherapy in Advanced NSCLC
NCT05137912 ·Status: UNKNOWN
-
Neo-adjuvant Treatment in Non-Small Cell Lung Cancer (NSCLC)
NCT01059188 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy, Radiation Therapy, and Gefitinib in Treating Patients With Stage III Non-Small Cell Lung Cancer
NCT00040794 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Outcomes of Patients With Resectable Non-Small Cell Lung Cancer Receiving Neoadjuvant Nivolumab Plus Chemotherapy in France
NCT06735781 ·Status: COMPLETED
-
A Study of Neoadjuvant Chemotherapy Plus Nivolumab Versus Neoadjuvant Chemotherapy Plus Placebo, Followed by Surgical Removal and Adjuvant Treatment With Nivolumab or Placebo for Participants With Surgically Removable Early Stage Non-small Cell Lung Cancer
NCT04025879 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Study of the Efficacy of an Investigational Drug in Adult Patients With Non Small-Cell Lung Cancer (NSCLC)
NCT00034957 ·Status: COMPLETED ·Phase: PHASE2
-
Trial of Neoadjuvant Docetaxel and Cisplatin for Resectable Non-Small Cell Lung Cancer
NCT00232206 ·Status: TERMINATED ·Phase: PHASE2
-
Neoadjuvant or Adjuvant Chemotherapy in Patients With Operable Non-small-cell Lung Cancer
NCT00913705 ·Status: COMPLETED ·Phase: PHASE3
-
Phase II Neoadjuvant Trial of a Continuous Infusion of Paclitaxel Plus Cisplatin Followed by Chest Radiotherapy for Patients With Stage III Non-Small Cell Lung Cancer
NCT00001499 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II Clinical Trial of Docetaxel, Oxaliplatin Combination Chemotherapy in Patients With Stage IIIB/IV Non-adenocarcinoma, Non-small Cell Lung Cancer (NSCLC) as Second-line Treatment
NCT01497041 ·Status: UNKNOWN ·Phase: PHASE2
-
An Investigational Immuno-therapy Study of Nivolumab Given After Surgery in Non-Small Cell Lung Cancer (NSCLC) Participants With Minimal Residual Disease
NCT03770299 ·Status: WITHDRAWN ·Phase: PHASE2
-
Preoperative Therapy in Patients With Stages IB, II, IIIA, and Selected IIIB Patients With Non-Small Cell Lung Cancer
NCT00193427 ·Status: COMPLETED ·Phase: PHASE2
-
Biomarkers in Predicting Treatment Response in Samples From Patients With Early-Stage Non-Small Cell Lung Cancer Previously Treated With Adjuvant Chemotherapy
NCT01595074 ·Status: NOT_YET_RECRUITING
-
Necitumumab in the Neoadjuvant Setting With Gemcitabine in Surgically Resectable - 14X-US-I001
NCT03574818 ·Status: TERMINATED ·Phase: PHASE2
-
S0342: Paclitaxel, Carboplatin, and Cetuximab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
NCT00085501 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin and Gemcitabine Combined With Celecoxib and/or Zileuton in Treating Patients With Advanced Non-Small Cell Lung Cancer
NCT00070486 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Chemotherapy in Non Small Cell Lung Cancer (NSCLC) Stages IB, IIA, IIB, and IIIA/T3
NCT00273507 ·Status: TERMINATED ·Phase: PHASE3
-
A Prospective Cohort Study of Neoadjuvant Chemotherapy Plus Sintillumab in the Treatment of Resectable NSCLC
NCT06485557 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Preoperative or Postoperative Therapy of Patients With Stages IB, II, IIIA Non-Small Cell Lung Cancer
NCT00193310 ·Status: COMPLETED ·Phase: PHASE2
-
Surgery With or Without Preoperative Chemotherapy in Treating Patients With Resectable Non-small Cell Lung Cancer
NCT00003159 ·Status: COMPLETED ·Phase: PHASE3
-
MK2206 and Erlotinib Hydrochloride in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Progressed After Previous Response to Erlotinib Hydrochloride Therapy
NCT01294306 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant MPDL3280A, Nab-paclitaxel and Carboplatin (MAC) in NSCLC
NCT02716038 ·Status: COMPLETED ·Phase: PHASE2
-
Adding Certolizumab to Chemotherapy + Nivolumab in People Who Have Lung Cancer That Can Be Treated With Surgery
NCT04991025 ·Status: RECRUITING ·Phase: PHASE2
-
Randomised Study Comparing Three Chemotherapy Regimens in Non-small Cell Lung Cancer
NCT00622349 ·Status: COMPLETED ·Phase: PHASE3
-
Radiation Therapy Plus Chemotherapy in Treating Patients With Non-small Cell Lung Cancer
NCT01134861 ·Status: COMPLETED ·Phase: PHASE3