MedTrace Logo

Physiological Responses to Exercise Tests in Primary Ciliary Dyskinesia Compared With Healthy Individuals

NCT05712798 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 46

Last updated 2024-07-01

No results posted yet for this study

Summary

The individuals with primary ciliary dyskinesia (PCD) have lower aerobic fitness and anaerobic performance than healthy individuals. Cardiopulmonary exercise test (CPET) provides an integrated assessment of integrative exercise responses involving the pulmonary, cardiovascular, hematopoietic, neuropsychological, and skeletal muscle systems that are not adequately reflected by measurement of the function of organ systems. Maximum oxygen consumption is measured by performing gas exchange analysis with CPET, offering an objective measure of cardiorespiratory fitness. The six-minute walk test (6MWT) and the shuttle walk test (SWT) are field tests that produce oxygen consumption results similar to those during CPET. There is a need to determine the physiological responses to CPET, SWT and 6MWT in individuals with PCD. Additionally, the physiological responses of individuals with PCD to different exercise tests will be compared with the responses of healthy individuals. Low aerobic capacity in individuals with PCD may affect the physical, emotional, and social lives of individuals. This influence may cause a decrease in the quality of life of individuals with PCD. The relationship between exercise capacity and quality of life in individuals with PSD will be investigated with this study.

Conditions

  • Primary Ciliary Dyskinesia

Interventions

OTHER

No intervention

No intervention

Sponsors & Collaborators

  • Hacettepe University

    lead OTHER

Principal Investigators

  • Deniz Inal-Ince · Hacettepe University

  • Ugur Ozcelik · Hacettepe University

  • Nagehan Emiralioglu · Hacettepe University

  • Melda Saglam · Hacettepe University

  • Naciye Vardar-Yagli · Hacettepe University

  • Ebru Calik-Kutukcu · Hacettepe University

  • Birce Sunman · Hacettepe University

  • Hazal Sonbahar-Ulu · Akdeniz University

  • Aslihan Cakmak · Hacettepe University

Eligibility

Min Age
8 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-10-07
Primary Completion
2023-10-07
Completion
2023-10-07

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05712798 on ClinicalTrials.gov