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Spheroidal Mesenchymal Stem Cells in Retinitis Pigmentosa

NCT05712148 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2023-02-03

No results posted yet for this study

Summary

Purpose: This prospective clinical case series aimed to evaluate the effect of suprachoroidal implantation of mesenchymal stem cells (MSCs) in the form of spheroids as a stem cell therapy for retinitis pigmentosa (RP) patients with relatively good visual acuity.

Methods: Fifteen eyes of 15 patients with RP who received suprachoroidal implantation of MSCs in the form of spheroids were included. Best corrected visual acuity (BCVA), 10-2 and 30-2 visual field examination and multifocal electroretinography (mfERG) recordings were recorded at baseline, postoperative first, third- and sixth-months during follow-up.

Conditions

Interventions

BIOLOGICAL

Stem cell implantation

Suprachoridal mesenchymal spheroidal stem cell implantation

Sponsors & Collaborators

  • Acibadem University

    lead OTHER

Principal Investigators

  • Berna Özkan, Professor · Acibadem University

  • Ercüment Ovalı, Professor · Acıbadem LabCell Cellular Therapy Center

Study Design

Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-10-11
Primary Completion
2022-01-30
Completion
2022-06-14

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05712148 on ClinicalTrials.gov