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A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

NCT05705531 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 190

Last updated 2026-05-05

No results posted yet for this study

Summary

This study assesses how blood cell growth patterns (clonal hematopoiesis) relate to heart health or cardiovascular disease (CVD) after treatment in patients with Hodgkin lymphoma. In some patients, cancer treatment at a young age may lead to later complications, including problems with heart health. Checking for blood cell growth patterns called therapy-related clonal hematopoiesis (t-CH) can help predict who might be at risk for heart health problems after Hodgkin lymphoma treatment. If doctors know who may be at greater risk for developing later heart complications, then they can more closely monitor those patients to prevent or detect heart complications early.

Conditions

  • Cardiovascular Disorder
  • Classic Hodgkin Lymphoma
  • Clonal Hematopoiesis

Interventions

PROCEDURE

Archive Sample Retrieval

Undergo collection of archived blood sample

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

OTHER

Electronic Health Record Review

Undergo medical record abstraction

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

OTHER

Survey Administration

Complete surveys

Sponsors & Collaborators

  • Children's Oncology Group

    lead NETWORK

Principal Investigators

  • Robert J Hayashi · Children's Oncology Group

Eligibility

Min Age
7 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-08-18
Primary Completion
2028-10-01
Completion
2028-10-01

Countries

  • United States
  • Canada

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05705531 on ClinicalTrials.gov