Roles of Some Non-classic Biomarkers in Pediatric Pneumonia
NCT05701605 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 120
Last updated 2023-01-27
Summary
The current work aims to:
1. Measure the levels of Neutrophil CD64 Receptor, Monocyte Human Leukocyte Antigen-DR (mHLA-DR), and Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) in children suffering from pneumonia.
2. Compare these levels to their levels in healthy control children.
3. Analyze the cut-off point, sensitivity, specificity, and area under the ROC curve of these biomarkers to test their abilities to early differentiate children with pneumonia from healthy control children.
4. Conclude or reject their possible use as diagnostic and/or prognostic markers in pediatric pneumonia.
Conditions
- Pneumonia in Children
Sponsors & Collaborators
-
Assiut University
lead OTHER
Principal Investigators
-
El-Sayed Khalil, Prof · Assiut University
-
Yasser Farouk, Assist prof · Assiut University
-
Khalid Mohany, Assist prof · Assiut University
Eligibility
- Min Age
- 1 Month
- Max Age
- 5 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-07-01
- Primary Completion
- 2024-01-01
- Completion
- 2024-06-01
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