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Three Different Cross-linking Protocols for Treatment of Pediatric Keratoconus

NCT05691335 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 97

Last updated 2023-03-31

No results posted yet for this study

Summary

comparison between standard cross-linking protocol and accelerated and transepithelial cross-linking

Conditions

  • Corneal Ectasia

Interventions

PROCEDURE

Standard CXL

Epithelium-off CXL performed by removal of corneal epithelium, instillation of riboflavin onto the cornea followed by UVA corneal irradiation for 30 minutes.

PROCEDURE

Accelerated CXL

Epithelium-off CXL performed by removal of corneal epithelium, instillation of riboflavin onto the cornea followed by UVA corneal irradiation for 5 minutes.

PROCEDURE

Transepithelial CXL

Epithelium-on CXL performed by instillation of riboflavin onto the cornea followed by UVA corneal irradiation for 5 minutes.

Sponsors & Collaborators

  • Sohag University

    lead OTHER

Principal Investigators

  • Mohammed Iqbal, MD, PhD · Sohag University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
12 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-06-01
Primary Completion
2023-01-01
Completion
2023-01-05

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05691335 on ClinicalTrials.gov