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Usefulness of PET-CT for Invasive Fungal Infection

NCT05688592 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 224

Last updated 2024-11-06

No results posted yet for this study

Summary

The goal of this national multicenter prospective cohort study is to learn about the added value of 18F-FDG (18F-2-fluoro-2-deoxy-D-glucose) PET-CT in invasive fungal disease management. The main questions it aims to answer are:

1. Does the use of 18F-FDG PET-CT allow a better characterization of invasive fungal infection (IFI) (performance) compared to the exclusive use of conventional radiological studies in terms of extension/staging and monitoring of response/follow-up ?
2. Does the systematic and protocolized use of 18F-FDG PET-CT in IFI allow a better management of patients with IFI and increase the prognostic value of the initial evaluation? Participants will undergo systematically a 18F-FDG PET-CT as part of the work-up of their invasive fungal disease. Researchers will compare the performance of 18F-FDG PET-CT with standard management without 18F-FDG PET-CT to see if adds value (diagnostic, prognostic, and changes in management).

Conditions

  • Invasive Fungal Infections

Interventions

PROCEDURE

PET-CT

This is a before-and-after study (not a clinical trial) * in the case of fungemia, 2 weeks after the initial staging 18F-FDG PET-CT. * in the case of focal IFIs, 2-4 and 12 weeks after the initial staging 18F-FDG PET-CT

Sponsors & Collaborators

  • Gilead Sciences

    collaborator INDUSTRY

  • Puerta de Hierro University Hospital

    lead OTHER

Principal Investigators

  • Ana Fernández Cruz, MDPhD · Hospital Puerta de Hierro-Majadahonda

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-27
Primary Completion
2024-10-31
Completion
2024-12-01

Countries

  • Spain

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05688592 on ClinicalTrials.gov