MedTrace Logo

Mitochondrial Membrane Protein Neurodegeneration (MPAN)

NCT05678790 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2

Last updated 2023-09-28

No results posted yet for this study

Summary

The purpose of this case study was to investigate the effects of therapeutic intervention in 9- and 12-year-old brothers with MPAN. The main hypothesis it aims to answer is:

-A 6-week balance and coordination focused rehabilitation program improves independence and gait parameters in patients with MPAN.

Conditions

  • MPAN

Interventions

OTHER

Passive Stretching

Sustained passive stretching of hamstring, tendo-achilles, and adductors 10 (30 s, with three repetitions, five times per week)

OTHER

Mobilization

Grade four mobilizations is a stretching motion performed at the talocrural joint with anterior-posterior gliding. Mobilization was performed once a day, 6 times a day, and 5 times a week, only on both deformed feet of the older sibling

OTHER

Muscle strengthening

Abdominal muscle strengthening exercises were given to both siblings once a day, 10 times a day, 5 times a week. In the supine position, the patients were asked to lie on their knees with the knees flexed. The hip extensors were trained in the prone position on the bed by resisting hip extension

OTHER

Balance and Coordination

The following exercises were applied 5 times a week, with 1o repetition once a day. * Standing on one leg in front of the mirror, * Tandem walking, * Rhythmic Dynamic Stabilization, * Swiss ball sitting (eyes open and closed), * Counting the alphabet or numbers while marching

Sponsors & Collaborators

  • Kirsehir Ahi Evran Universitesi

    lead OTHER

Principal Investigators

  • Figen TUNCAY · Kirsehir Ahi Evran Universitesi

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
9 Years
Max Age
14 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-01
Primary Completion
2023-09-28
Completion
2023-09-28

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05678790 on ClinicalTrials.gov