Birth Weight-discordance in Twins Pregnancy: a Multicenter Retrospective Study

Summary

The rate of twin pregnancies in China has increased by 50 percent over the past decade and now stands at about 3 percent. This is significantly higher than the European and American countries. There are significant differences in birth weight of some newborns, that is, birth weight-discordance in twin pregnancies (BWDT). BWDT was significantly associated with fetal death, preterm birth, neonatal death, and neonatal complications. Existing studies mainly focus on the perinatal outcomes of mothers and infants with BWDT, or are reported from small samples in developed countries. The investigators are aware of the need to further explore the occurrence of birth weight inconsistency and adverse neonatal outcomes in China with a large sample. Through retrospective study design, the investigators will collect clinical data of live twin births at multiple study sites, investigate the incidence of BWDT, and analyze its adverse outcomes.

Conditions

• Twin; Pregnancy, Affecting Fetus or Newborn

Sponsors & Collaborators

• Peking University Third Hospital

  collaborator OTHER

• The Affiliated Hospital of Inner Mongolia Medical University

  collaborator OTHER

• The Third Hospital Of BaoGang Group

  collaborator UNKNOWN

• Lanzhou University Second Hospital

  collaborator OTHER

• Yan'an University Affiliated Hospital

  collaborator OTHER

• Xiamen University Women and Children's Hospital

  collaborator UNKNOWN

• Xinxiang Central Hospital

  collaborator OTHER

• Central Hospital of Xiaogan

  collaborator OTHER

• Guizhou Medical University Affiliated Hospital

  collaborator UNKNOWN

• Sichuan Jinxin Women and Children's Hospital

  collaborator UNKNOWN

• The First Affiliated Hospital of Shaoyang University

  collaborator UNKNOWN

• First Affiliated Hospital of Jinan University

  collaborator OTHER

• First Affiliated Hospital of Shantou University Medical College

  collaborator OTHER

• Second Affiliated Hospital of Shantou University Medical College

  collaborator OTHER

• The Second People's Hospital of GuangDong Province

  collaborator OTHER

• Dongguan People's Hospital

  collaborator OTHER_GOV

• Dongguan Binhai Bay Central Hospital

  collaborator UNKNOWN

• Zhongshan People's Hospital, Guangdong, China

  collaborator OTHER

• Huizhou Municipal Central Hospital

  collaborator OTHER

• Yuebei People's Hospital

  collaborator OTHER

• The Third Affiliated Hospital of Guangzhou Medical University

  lead OTHER

Eligibility

Min Age

1 Day

Max Age

28 Days

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2020-09-10

Primary Completion

2022-10-01

Completion

2022-11-25

Countries

• China

Study Locations