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Laryngeal Cryotherapy for Refractory Neurogenic Cough

NCT05665244 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 28

Last updated 2026-01-30

No results posted yet for this study

Summary

This study aims to evaluate the safety and efficacy of upper aerodigestive tract cryotherapy treatment in patients with refractory neurogenic cough in a prospective pilot study with a validated patient reported outcome measure

Conditions

  • Upper-Airway Cough Syndrome

Interventions

PROCEDURE

Laryngeal cryotherapy

Laryngeal cryotherapy is the therapeutic freezing of tissue in the throat to numb the overactive sensory nerves in the throat. This technique is believed to reduce cough symptoms in this study.

DEVICE

Cryoprobe

Cryoprobe is FDA approved for use for the destruction of unwanted tissue along the respiratory tract

Sponsors & Collaborators

  • University of Texas Southwestern Medical Center

    lead OTHER

Principal Investigators

  • Shumon Dhar, MD · University of Texas Southwestern Medical Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-12-26
Primary Completion
2027-02-28
Completion
2027-02-28
FDA Device
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05665244 on ClinicalTrials.gov