Improving Neurological Outcome for Acute Basilar Artery Occlusion With Sufficient Recanalization After Thrombectomy by Intraarterial Tenecteplase (INSIST-IT)

NCT05657457 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 145

Last updated 2025-07-02

No results posted yet for this study

Summary

The potential benefit of intraarterial tenecteplase in acute basilar artery occlusion (BAO) patients with successful reperfusion following endovascular treatment (EVT) has not been studied. The current study aimed to explore the efficacy and safety of intraarterial tenecteplase in acute BAO patients with successful reperfusion after EVT.

Conditions

  • Stroke, Ischemic

Interventions

DRUG

Tenecteplase

intra-arterial tenecteplase

Sponsors & Collaborators

  • Cerebrovascular Disease Collaboration & Innovation Alliance of Liaoning

    collaborator UNKNOWN
  • General Hospital of Shenyang Military Region

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-03-21
Primary Completion
2025-05-18
Completion
2025-05-18

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05657457 on ClinicalTrials.gov