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Promoting Cognitive Resilience and Reducing Frailty in Older Veterans With Bright Light Therapy

NCT05631236 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 43

Last updated 2026-01-27

No results posted yet for this study

Summary

Frailty is a multifactorial syndrome characterized by vulnerability to stressors that is intricately linked to cognitive impairment and mortality risk. Bright light therapy (BLT) reduces circadian disturbances by resynchronizing the hypothalamic biological clock via specific wavelengths of light. Human trials have demonstrated that BLT improves sleep quality and cognitive function in older adults. However, BLT has not been examined for use in older Veteran populations, particularly the impact on frailty. This randomized trial will assess the feasibility of employing BLT to study impacts on frailty, cognition, and sleep in older Veterans. Findings from this pilot will establish the power and effect size necessary for larger trials to support the use of BLT as readily available home-based treatment to improve healthspan of Veterans.

Conditions

  • Veteran Aged 65 and Older

Interventions

DEVICE

Bright Light Therapy (AYO Glasses)

Bright light glasses that emit a more intense therapeutic blue light.

DEVICE

Bright Light Therapy (AYO Glasses)

Bright light glasses that emit a non-therapeutic blue light.

Sponsors & Collaborators

  • VA Office of Research and Development

    lead FED

Principal Investigators

  • Bruce R. Troen, MD · Kansas City VA Medical Center, Kansas City, MO

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-01-29
Primary Completion
2026-06-30
Completion
2026-06-30
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05631236 on ClinicalTrials.gov