The 'Wearing Off' Effect of DMT
NCT05627271 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 39
Last updated 2023-06-01
Summary
This is a non-interventional, cross-sectional, qualitative study in which patients diagnosed with MS and clinicians with experience treating MS will be interviewed regarding patient experiences with the wearing off effect from ocrelizumab, natalizumab, and ofatumumab
Conditions
Interventions
- OTHER
-
ocrelizumab
Non-interventional, cross-sectional, qualitative study. There is no treatment allocation. Patients prescribed with Disease-modifying therapy in the commercial setting are eligible to enroll into this study.
- OTHER
-
natalizumab
Non-interventional, cross-sectional, qualitative study. There is no treatment allocation. Patients prescribed with Disease-modifying therapy in the commercial setting are eligible to enroll into this study.
- OTHER
-
ofatumumab
Non-interventional, cross-sectional, qualitative study. There is no treatment allocation. Patients prescribed with Disease-modifying therapy in the commercial setting are eligible to enroll into this study.
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Novartis Pharmaceuticals · Novartis Pharmaceuticals
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-01-10
- Primary Completion
- 2023-04-20
- Completion
- 2023-04-20
Countries
- Switzerland
Study Locations
More Related Trials
-
Characterization of Early Patients Initiating Ofatumumab for Treatment of Multiple Sclerosis.
NCT05576779 ·Status: COMPLETED
-
A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation
NCT05090371 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
The Wearing-off Phenomenon of Ocrelizumab in Patients With Multiple Sclerosis
NCT04478591 ·Status: COMPLETED
-
Comparative Study of High-Efficacy Disease Modifying Treatment of Relapsing Multiple Sclerosis
NCT06159712 ·Status: RECRUITING ·Phase: NA
-
Open Label Randomized Multicenter to Assess Efficacy & Tolerability of Ofatumumab 20mg vs. First Line DMT in RMS
NCT04788615 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)
NCT02861014 ·Status: COMPLETED ·Phase: PHASE3
-
Symptom Burden in Patients Treated With Ocrelizumab for Multiple Sclerosis
NCT04855617 ·Status: COMPLETED
-
Time and Motion Study for Ocrelizumab and Ofatumumab Administration in Relapsing Multiple Sclerosis
NCT04676555 ·Status: COMPLETED
-
Short-term B-cell Depletion in Relapsing Multiple Sclerosis
NCT03853746 ·Status: COMPLETED ·Phase: PHASE4
-
Study of Efficacy and Safety of Ofatumumab in Relapsing Multiple Sclerosis (RMS) Patients in China
NCT05199571 ·Status: COMPLETED ·Phase: PHASE4
-
Reduced Oligodendrocyte-specific Cytotoxicity and Ofatumumab Treatment
NCT05171972 ·Status: COMPLETED
-
A Cross-sectional Study to Assess the Effectiveness and Safety of Ofatumumab (Kesimpta®) in Patients With Relapsing Multiple Sclerosis in the Spanish Clinical Practice
NCT06251986 ·Status: COMPLETED
-
Real-world Data of Ocrelizumab in Multiple Sclerosis in LATAM
NCT03784547 ·Status: UNKNOWN
-
A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)
NCT02637856 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Describe the Switching From a First- or Second-line Disease Modifying Therapy (DMT) to Ozanimod in Participants With Relapsing Remitting Multiple Sclerosis (RRMS)
NCT05658601 ·Status: COMPLETED
-
Comparison of Oral Molecules Preventing Relapses in Multiple Sclerosis
NCT03302442 ·Status: COMPLETED
-
Immune Profiling During Ocrelizumab Treatment in Multiple Sclerosis
NCT03138525 ·Status: COMPLETED
-
POC-MD MRI-based Trial in Relapsing-remitting Multiple Scler
NCT01051817 ·Status: COMPLETED ·Phase: PHASE2
-
Effects of Ofatumumab Treatment on Immune Cells and Meningeal Lymphatic Drainage in Patients With Demyelinating Diseases
NCT05414487 ·Status: UNKNOWN
-
A Survey to Evaluate Early Experience From Patient and Care Partner on Injection and Device for KESIMPTA® Indicated for Multiple Sclerosis
NCT05334472 ·Status: COMPLETED
-
Understanding the 'Durable Effect' Concept of B-cell Modulating Therapies
NCT06586177 ·Status: RECRUITING
-
A Study of Multiple Sclerosis Routine Clinical Practice: Impact on Adherence and Clinical Outcomes of Ofatumumab Treated Patients
NCT06897657 ·Status: COMPLETED
-
Discontinuation of Disease Modifying Therapies (DMTs) in Multiple Sclerosis (MS): Extension of the DISCOMS Study
NCT04754542 ·Status: COMPLETED
-
Impact of Disease Modifying Therapies (DMTs) and Associated Support Services in Relapsing Multiple Sclerosis (RMS) Patients
NCT01601119 ·Status: COMPLETED
-
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a New Maintenance Dosing Regimen of Ofatumumab
NCT06869785 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3