Trial Outcomes & Findings for Does What You Eat Affect Your Brain (NCT NCT05626907)
NCT ID: NCT05626907
Last Updated: 2026-07-17
Results Overview
T2 relaxation time as measured by brain MRI
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
36 participants
Primary outcome timeframe
7 days of diet intervention
Results posted on
2026-07-17
Participant Flow
N=2 were enrolled, but became ineligible at or following the first study visit.
Participant milestones
| Measure |
Assigned Diet #1
Assigned diet 100% of daily caloric need
|
Assigned Diet #2
Assigned diet 130% of daily caloric need.
|
Assigned Diet #3
Assigned diet 150% of daily caloric need.
|
|---|---|---|---|
|
Overall Study
STARTED
|
13
|
10
|
11
|
|
Overall Study
COMPLETED
|
12
|
10
|
11
|
|
Overall Study
NOT COMPLETED
|
1
|
0
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Does What You Eat Affect Your Brain
Baseline characteristics by cohort
| Measure |
Assigned Diet #1
n=13 Participants
Assigned diet 100% of daily caloric need
|
Assigned Diet #2
n=10 Participants
Assigned diet 130% of daily caloric need.
|
Assigned Diet #3
n=11 Participants
Assigned diet 150% of daily caloric need.
|
Total
n=34 Participants
Total of all reporting groups
|
|---|---|---|---|---|
|
Age, Continuous
|
29.5 year
STANDARD_DEVIATION 5.5 • n=20 Participants
|
34.2 year
STANDARD_DEVIATION 4.0 • n=20 Participants
|
30.0 year
STANDARD_DEVIATION 4.9 • n=40 Participants
|
31.1 year
STANDARD_DEVIATION 5.2 • n=5 Participants
|
|
Sex: Female, Male
Female
|
6 Participants
n=20 Participants
|
5 Participants
n=20 Participants
|
5 Participants
n=40 Participants
|
16 Participants
n=5 Participants
|
|
Sex: Female, Male
Male
|
7 Participants
n=20 Participants
|
5 Participants
n=20 Participants
|
6 Participants
n=40 Participants
|
18 Participants
n=5 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
0 Participants
n=20 Participants
|
0 Participants
n=20 Participants
|
1 Participants
n=40 Participants
|
1 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Asian
|
2 Participants
n=20 Participants
|
3 Participants
n=20 Participants
|
5 Participants
n=40 Participants
|
10 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=20 Participants
|
0 Participants
n=20 Participants
|
0 Participants
n=40 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Black or African American
|
0 Participants
n=20 Participants
|
0 Participants
n=20 Participants
|
1 Participants
n=40 Participants
|
1 Participants
n=5 Participants
|
|
Race (NIH/OMB)
White
|
9 Participants
n=20 Participants
|
6 Participants
n=20 Participants
|
4 Participants
n=40 Participants
|
19 Participants
n=5 Participants
|
|
Race (NIH/OMB)
More than one race
|
2 Participants
n=20 Participants
|
1 Participants
n=20 Participants
|
0 Participants
n=40 Participants
|
3 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=20 Participants
|
0 Participants
n=20 Participants
|
0 Participants
n=40 Participants
|
0 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
0 Participants
n=20 Participants
|
2 Participants
n=20 Participants
|
2 Participants
n=40 Participants
|
4 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
12 Participants
n=20 Participants
|
8 Participants
n=20 Participants
|
9 Participants
n=40 Participants
|
29 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
1 Participants
n=20 Participants
|
0 Participants
n=20 Participants
|
0 Participants
n=40 Participants
|
1 Participants
n=5 Participants
|
|
BMI
|
26.5 kg/m2
STANDARD_DEVIATION 1.2 • n=20 Participants
|
26.7 kg/m2
STANDARD_DEVIATION 1.3 • n=20 Participants
|
28.0 kg/m2
STANDARD_DEVIATION 1.9 • n=40 Participants
|
27.1 kg/m2
STANDARD_DEVIATION 1.6 • n=5 Participants
|
PRIMARY outcome
Timeframe: 7 days of diet interventionT2 relaxation time as measured by brain MRI
Outcome measures
| Measure |
Assigned Diet #1
n=13 Participants
Assigned diet 100% of daily caloric need
|
Assigned Diet #2
n=10 Participants
Assigned diet 130% of daily caloric need.
|
Assigned Diet #3
n=11 Participants
Assigned diet 150% of daily caloric need.
|
|---|---|---|---|
|
Hypothalamic Gliosis
|
104.3 ms
Standard Deviation 5.4
|
109.6 ms
Standard Deviation 8.0
|
102.9 ms
Standard Deviation 5.1
|
Adverse Events
Assigned Diet #1
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Assigned Diet #2
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Assigned Diet #3
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place