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Ophthalmologic Outcomes in Patients With Carotid Artery Stenosis

NCT05623293 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2022-11-21

No results posted yet for this study

Summary

The retinal vessels have been shown to reflect vascular changes inherent to systemic pathologies, even when no ocular disease is identified. As such, the eye's vasculature is ableto serve as a window to the vascular health of the human body and a means of assessing systemic endothelial function. Optical coherence tomography angiography (OCTA) employs optical means to image all the retinal vascular layers and the choroid, providing an extremely detailed image of the microvascular network in a fast, reproducible and totally non-invasive way. As such, it is currently the best non-invasive way of having an image of human capillaries. Recently, OCTA has been used to study the retinal vessels' structure and function in several cardiovascular diseases. As an example of its predictive potential, reduced retinal microvascular density has been associated with the cardiovascular risk profile in patients admitted to the hospital for an acute coronary syndrome. Recent studies have also shown the retinal microvasculature density to be reduced in patients with carotid artery disease (CAD), namely carotid stenosis, and that endarterectomy increases retinal flow and vessel density.

Conditions

  • Choroid Disease
  • Carotid Stenosis
  • Carotid Atherosclerosis
  • Retinal Disease

Interventions

DIAGNOSTIC_TEST

eye - Optcial coherence tomography

pre and postoperative

Sponsors & Collaborators

  • Hospital Sao Joao

    collaborator OTHER

  • Universidade do Porto

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-01
Primary Completion
2023-12-31
Completion
2023-12-31

Countries

  • Portugal

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05623293 on ClinicalTrials.gov