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The Effect of tDCS on Emotion Recognition and EEG

NCT05623072 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 56

Last updated 2023-09-06

No results posted yet for this study

Summary

Purpose and Importance of the Project: Emotion recognition, which is defined as the process of interpreting an individual's emotional state by looking at their facial expressions, is important in maintaining social relations and communication in a healthy way. Difficulties in emotion recognition can be seen in various neurodevelopmental or psychiatric disorders. The ventromedial prefrontal cortex (vmPFC) is one of the regions that is important in the function of emotion recognition from facial expressions. Transcranial Direct Current Stimulation (tDCS) is a non-invasive, painless method of brain stimulation that provides either excitatory or inhibitory effects on different parts of the brain. When the literature is examined, it is seen that studies on the effectiveness of tDCS on emotion recognition are limited and stimulation is generally applied to the right or left dorsolateral prefrontal cortex areas in these studies. On the other hand, no study has been found examining the effect of stimulation of the ventromedial prefrontal cortex on emotion recognition. In this study, it is aimed to investigate the effect of anodal stimulation of the ventromedial prefrontal cortex, which is significantly related to emotion recognition skills, on emotion recognition and EEG oscillations.

Methods: It is an experimental, randomised controlled trial. The data will be collected with the convenience sampling method from healthy and volunteer participants. The matched-group design method will be used. As a result of the power analysis, it was determined that the current study should be done with at least 34 participants. In the study, it is aimed to include a total of 60 participants in the experimental (tDCS) and control (sham) groups. Measurement instruments are "Informed Voluntary Consent Form"; "Demographic Information Form"; "Edinburgh Hand Preference Survey"; "Beck Depression Scale"; "Amsterdam Dynamic Facial Expression Set - Bath Intensity Variations (ADFES-BIV)"; "Mind-Reading Test"; EEG and tDCS devices. Participants will be subjected to the emotion recognition task before and after the tDCS. In addition, resting state EEG recordings will be taken before and after the tDCS from 34 participants.

Conditions

  • Emotion Recognition

Interventions

DEVICE

Active tDCS

20 min, 2 milliampere (mA), Anodal tDCS in vmPFC

DEVICE

Sham tDCS

20 min, vmPFC Sham tDCS

Sponsors & Collaborators

  • Istanbul Medipol University Hospital

    lead OTHER

Principal Investigators

  • Lütfü Hanoğlu, Prof. Dr. · Medipol University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-12-15
Primary Completion
2023-04-15
Completion
2023-06-15

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05623072 on ClinicalTrials.gov