A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 In Participants With Osteoarthritis Pain
NCT05620563 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 147
Last updated 2024-06-26
Summary
The main purpose of this study is to evaluate the efficacy and safety of LY3857210 in participants with Osteoarthritic Pain. This trial is part of the chronic pain master protocol, H0P-MC-CPMP (NCT05986292), which is a protocol to accelerate the development of new treatments for chronic pain.
Conditions
Interventions
- DRUG
-
LY3857210
Administered orally
- DRUG
-
Administered orally
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST) · Eli Lilly and Company
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-11-22
- Primary Completion
- 2023-06-05
- Completion
- 2023-06-12
- FDA Drug
- Yes
Countries
- United States
- Puerto Rico
Study Locations
More Related Trials
-
A Study of LY2828360 in Patients With Osteoarthritic Knee Pain
NCT01319929 ·Status: COMPLETED ·Phase: PHASE2
-
Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee
NCT01111045 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Evaluating the Safety, Tolerability, and Efficacy of SM04690 Injected in the Target Knee Joint of Moderately to Severely Symptomatic Osteoarthritis Subjects
NCT02536833 ·Status: COMPLETED ·Phase: PHASE2
-
Low Dose Naltrexone for Chronic Pain in Osteoarthritis and Inflammatory Arthritis
NCT04115020 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Phase II Study Looking at Moderate to Severe Osteoarthritis Knee Pain
NCT00394563 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Assess the Safety and Efficacy of an Investigational Drug (MK-686) in Patients With Osteoarthritis (0686-006)
NCT00296569 ·Status: COMPLETED ·Phase: PHASE2
-
A Single-Blind Placebo Run-in Study of Duloxetine for Activity-Limiting Osteoarthritis Pain
NCT00609557 ·Status: COMPLETED ·Phase: PHASE4
-
Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee
NCT00689273 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Bone Health Study of SM04690 for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis
NCT03727022 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of MT-5547 in Patients With Osteoarthritis Accompanied by Moderate to Severe Pain
NCT03245008 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Effect of Etoricoxib to Treat Chronic Low Back Pain (0663-041)
NCT00393354 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment for Patients With Osteoarthritis (OA)
NCT00110942 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 1, Dose Escalation Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SM04690 in Moderate to Severe Knee Osteoarthritis (OA)
NCT02095548 ·Status: COMPLETED ·Phase: PHASE1
-
Study of PIPE-791 for Subjects With Chronic Osteoarthritis Pain or Chronic Low Back Pain
NCT06810245 ·Status: COMPLETED ·Phase: PHASE1
-
Low Dose Naltrexone for Chronic Pain From Arthritis
NCT03008590 ·Status: COMPLETED ·Phase: PHASE2
-
A Proof-of-concept Study to Examine QUC398 in Participants With Knee OA
NCT05462990 ·Status: TERMINATED ·Phase: PHASE2
-
Effect of Etoricoxib to Treat Chronic Low Back Pain (0663-042)
NCT00393211 ·Status: COMPLETED ·Phase: PHASE3
-
Phase II Study of CG100649 for Primary Osteoarthritis in Male Subjects
NCT00530452 ·Status: UNKNOWN ·Phase: PHASE2
-
Study Evaluating AGG-523 in Subjects With Osteoarthritis
NCT00427687 ·Status: COMPLETED ·Phase: PHASE1
-
Open Label Safety and Tolerability Study of COV155 in Subjects With Osteoarthritis (OA) or Chronic Low Back Pain (CLBP)
NCT01722864 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Duloxetine (LY248686) in Participants With Chronic Osteoarthritis and Knee Pain in Japan
NCT02248480 ·Status: COMPLETED ·Phase: PHASE3
-
First-in-human, Safety, Tolerability and Pharmacokinetics Study of LRX712 in Osteoarthritic Patients
NCT03355196 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Chronic, Moderate to Severe Osteoarthritis Knee Pain
NCT02558439 ·Status: COMPLETED ·Phase: PHASE2
-
A Pilot Study Assessing the Treatment Responsiveness of a Novel Osteoarthritis Stiffness Scale
NCT03570554 ·Status: COMPLETED ·Phase: PHASE2
-
Brain Morphometry in OA Patients Treated With Duloxetine
NCT02903238 ·Status: COMPLETED ·Phase: NA