The Fast-track Centre for Hip and Knee Replacement Database

Summary

This is a prospective study-registry on preoperative patient characteristics and postoperative complications in patients having fast-track hip and knee replacement surgery in 8 Danish dedicated arthroplasty departments from all five health regions in Denmark. The registry consists of detailed patient and physician reported preoperative characteristics and including prescribed medication and lab results. Follow-up is based on electronical medical records by dedicated nurses with physician backup and includes Clavien-Dindo and Comprehensive Complication Index scoring. All patients having day-surgery also completes a patient reported questionaire on health-care utilization and return to work by day 30. Finally, a machine-learning algorithm for identification of "high-risk" patients based on he preoperative data is included.

Conditions

• Hip
• Knee
• Fast-track Surgery
• Enhanced Recovery After Surgery
• Perioperative Medicine
• Ambulatory Surgical Procedures
• Perioperative/Postoperative Complications
• Patient Satisfaction

Interventions

PROCEDURE

Day-surgery

Standard surgical procedure but with planned discharge on day of surgery

PROCEDURE

High-risk patient

Standard fast-track procedure but with additional perioperative measures dependent on risk-profile.

PROCEDURE

Main Group

Standard fast-track procedure according to usual standard of care and discharge when fulfilling functional discharge criteria

Sponsors & Collaborators

• The Novo Nordic Foundation

  collaborator OTHER

• Gødstrup Hospital

  collaborator OTHER

• Sygehus Lillebaelt

  collaborator OTHER

• Svendborg Hospital

  collaborator OTHER

• University Hospital, Gentofte, Copenhagen

  collaborator OTHER

• Naestved Hospital

  collaborator OTHER

• Bispebjerg Hospital

  collaborator OTHER

• Aalborg University Hospital

  collaborator OTHER

• Hvidovre University Hospital

  collaborator OTHER

• Region of Southern Denmark

  collaborator OTHER

• Rigshospitalet, Denmark

  lead OTHER

Principal Investigators

• Henrik Kehlet, M.D. · Section for Surgical Pathophysiology, Rigshospitalet, University of Copenhagen

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-09-01

Primary Completion

2025-12-31

Completion

2027-12-31

Countries

• Denmark

Study Locations