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Endothelial Glycocalyx Damage in Brain Death Organ Donors

NCT05609123 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2026-05-01

No results posted yet for this study

Summary

The study aims the assessment of endothelial glycocalyx (EG) degradation in deceased organ donors. There is a lack of organs for the transplantation program. By the description of the EG status, we can open room for organ optimization before transplantation and improve the organ function after transplantation in marginal donors.

Conditions

  • Brain Damage Due to Hypoxia
  • Organ Donors
  • Organ Transplant Failure or Rejection

Interventions

DIAGNOSTIC_TEST

Endothelial glycocalyx damage assessment

Degradation products of endothelial glycocalyx will be assessed in the blood and urine.

Sponsors & Collaborators

  • University Hospital Hradec Kralove

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-01
Primary Completion
2027-12-31
Completion
2027-12-31

Countries

  • Czechia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05609123 on ClinicalTrials.gov