MRI Screening in Men at High Risk of Developing Prostate Cancer
NCT05608694 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 250
Last updated 2026-03-02
Summary
The purpose of this study is to determine whether or not Magnetic Resonance Images (MRI) will identify high-grade cancers earlier and more frequently in men at high risk of developing prostate cancer.
Conditions
- Prostate Cancer Screening
Interventions
- OTHER
-
Prostate MRI
Group placement is determined by GRS score, Family history, and germline testing
Sponsors & Collaborators
-
University of Chicago
lead OTHER
Principal Investigators
-
Scott Eggener, MD · University of Chicago
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- SCREENING
- Masking
- NONE
- Model
- FACTORIAL
Eligibility
- Min Age
- 18 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-03-02
- Primary Completion
- 2037-03-01
- Completion
- 2039-03-01
Countries
- United States
Study Locations
More Related Trials
-
Upright MRI for Prostate Cancer Screening
NCT03474913 ·Status: RECRUITING
-
MRI Risk Maps for Prostate Cancer Diagnosis Using Targeted Biopsy
NCT05710380 ·Status: RECRUITING ·Phase: NA
-
Prostate Cancer Detection Screening MRI Protocol
NCT04175730 ·Status: COMPLETED ·Phase: NA
-
MRI in Diagnosing Prostate Cancer
NCT01292291 ·Status: UNKNOWN ·Phase: NA
-
Contrast Enhanced MRI of the Prostate
NCT02245282 ·Status: COMPLETED
-
Developing an Imaging-Based Tool to Identify Areas for Prostate Cancer Biopsy
NCT03585660 ·Status: COMPLETED ·Phase: NA
-
PSMA PET Scan and mpMRI for Prostate Cancer Detection
NCT05820724 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer
NCT06398639 ·Status: RECRUITING ·Phase: NA
-
Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort
NCT05384535 ·Status: RECRUITING ·Phase: NA
-
Magnetic Resonance Spectroscopic Imaging of the Prostate at 3 Tesla
NCT00588679 ·Status: COMPLETED ·Phase: NA
-
Men at High Genetic Risk for Prostate Cancer
NCT03805919 ·Status: RECRUITING
-
PET/MRI for the Staging of Newly Diagnosed Prostate Cancer
NCT03392181 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
High Resolution MRI Study for Prostate Cancer
NCT03292874 ·Status: COMPLETED ·Phase: NA
-
MRI Versus PSA in Prostate Cancer Screening
NCT02799303 ·Status: UNKNOWN ·Phase: NA
-
Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer
NCT04692675 ·Status: RECRUITING ·Phase: NA
-
PSMA-Targeted 18F-DCFPyL PET/MRI for the Detection of Prostate Cancer
NCT04910425 ·Status: WITHDRAWN ·Phase: PHASE2
-
Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer
NCT03976843 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Diagnosing the Extent of Disease in Patients With Prostate Cancer
NCT00032058 ·Status: COMPLETED ·Phase: NA
-
MRI Before Biopsy in Diagnosing Patients With Prostate Cancer
NCT02131207 ·Status: TERMINATED
-
Magnetic Resonance Imaging in Detecting Cancer Progression in Patients With Early Stage Prostate Cancer Undergoing Active Surveillance
NCT00796874 ·Status: WITHDRAWN ·Phase: NA
-
Integrated Genomic Prostate Score With MRI Targeted Prostate Biopsies
NCT04541030 ·Status: ACTIVE_NOT_RECRUITING
-
Prostate Cancer Screening in Men With Germline BRCA2 Mutations
NCT02154672 ·Status: COMPLETED
-
Evaluation of a Multimodal Strategy for Early Diagnosis of Men at High Genetic Risk of Prostate Cancer
NCT05333432 ·Status: WITHDRAWN ·Phase: NA
-
68Ga-PSMA PET/MRI in Conjunction With mpMRI for Evaluating Prospective Prostate Cancer Risk
NCT06494696 ·Status: RECRUITING
-
Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life
NCT06171269 ·Status: RECRUITING ·Phase: NA