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Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain

NCT05607381 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2026-02-03

No results posted yet for this study

Summary

The purpose of this research study is to see how a mindfulness meditation-based intervention affects pain. Specifically, we are interested in understanding the pain-relieving brain mechanisms of mindfulness meditation-based therapy for patients with opioid-treated chronic low back pain.

Conditions

  • Low Back Pain
  • Opioid Use

Interventions

BEHAVIORAL

Meditation

Participants will complete 8 sessions of meditation training with therapy as a means of coping with chronic pain and opioid-related issues.

OTHER

Usual care

Participants will receive usual care for chronic low back pain (e.g., analgesic medication, pain management consultant from a physician, physical therapy, etc.).

Sponsors & Collaborators

Principal Investigators

  • Eric Garland, PhD · University of Utah

  • Fadel Zeidan, PhD · University of California, San Diego

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-11-30
Primary Completion
2027-04-30
Completion
2027-06-30

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05607381 on ClinicalTrials.gov