A Study of Camrelizumab in Combination With Anlotinib in Subjects Advanced Ovarian Clear Cell Carcinoma
NCT05600998 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2022-11-01
Summary
This study is prospective ,open-label, single-center phase II clinical study. Target population is patients with advanced (stage III-IV) ovarian clear cell carcinoma. Study objective is to evaluate effectiveness response of Camrelizumab + anlotinib in subjects with advanced ovarian clear cell carcinoma Camrelizumab is a humanized anti-PD1 IgG4 monoclonal antibody.
Conditions
Interventions
- DRUG
-
Camrelizumab
Subjects will receive carilizumab every three weeks, with alozantinib 20 mg orally daily for 9 weeks
Sponsors & Collaborators
-
Peking University Third Hospital
lead OTHER
Principal Investigators
-
Hongyan Guo, Doctor · Peking University Third Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-10-30
- Primary Completion
- 2023-09-30
- Completion
- 2024-02-28
More Related Trials
-
Anlotinib Combined With Carboplatin/Paclitaxel as First-line Treatment in Patients With Advanced Ovarian Cancer
NCT04807166 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
QL1706 Combined With Chemotherapy and Anlotinib for the Treatment of Recurrent Ovarian Cancer
NCT07286240 ·Status: RECRUITING ·Phase: PHASE2
-
Anlotinib Combined With Dose-reduced Olaparib in Patients With Platinum-Sensitive Recurrent Ovarian Cancer
NCT04566952 ·Status: UNKNOWN ·Phase: PHASE2
-
ONC-392 and Pembrolizumab in Platinum Resistant Ovarian Cancer
NCT05446298 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
PD-1 Antibody Combined Neoadjuvant Chemotherapy for Ovarian Cancer
NCT04815408 ·Status: UNKNOWN ·Phase: PHASE2
-
SHR - A1811 Injection in the Treatment of Platinum-sensitive Recurrent Ovarian Cancer
NCT06990516 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
The Culture of Advanced or Recurrent Ovarian Cancer Organoids and Drug Screening
NCT05290961 ·Status: UNKNOWN
-
Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery
NCT04498117 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Phase 2, Open-label, Single-arm Study Of Autologous M-CENK Adoptive Cell Therapy And N-803 (IL-15 Superagonist) In Combination With Gemcitabine In Participants With Recurrent Platinum-Resistant High-Grade Ovarian Cancer
NCT06710288 ·Status: RECRUITING ·Phase: PHASE2
-
A Phase II Trial to Explore Niraparib and Anlotinib Maintenance Retreatment in Platinum-Sensitive Recurrent Ovarian Cancer Patients Previously Treated With PARPi
NCT05385068 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Pembrolizumab With or Without CC-486 in Patients With Platinum-resistant Ovarian Cancer
NCT02900560 ·Status: TERMINATED ·Phase: PHASE2
-
Olaparib Monotherapy and Olaparib + Pembrolizumab Combination Therapy for Ovarian Cancer
NCT04417192 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Pan-immunotherapy in Patients With Relapsed/Refractory Ovarian Cancer
NCT03989336 ·Status: COMPLETED ·Phase: PHASE2
-
Anlotinib for Patients With Platinum Resistant or Refractory Ovarian Cancer
NCT03924882 ·Status: UNKNOWN ·Phase: PHASE2
-
A Clinical Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsules Versus Paclitaxel as Weekly Treatment of Relapsed Platinum-resistant Ovarian Cancer
NCT05145218 ·Status: UNKNOWN ·Phase: PHASE3
-
A Phase 1b Study of Sevacizumab in Combination With Chemotherapy in Chinese Patients With Platinum-Resistant Recurrent Ovarian Cancer.
NCT03763123 ·Status: UNKNOWN ·Phase: PHASE1
-
Niraparib Plus Anlotinib for Recurrent Ovarian Cancer
NCT05311579 ·Status: UNKNOWN ·Phase: PHASE2
-
Adebrelimab Combined With Fuzuloparib in the Treatment of Patients With Recurrent Platinum-resistant Ovarian Cancer.
NCT05753826 ·Status: RECRUITING ·Phase: PHASE2
-
Aribulin Combined With Carboplatin and Bevacizumab in the Treatment of Ovarian Cancer
NCT05965141 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Dose Escalation, Safety and Activity Study of CDX-014 in Patients With Renal Cell Carcinoma and Ovarian Clear Cell Carcinoma
NCT02837991 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of Pembrolizumab With Standard Treatment in Patients With Recurrent Platinum-resistant Ovarian Cancer
NCT02608684 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of SHR-A1921 With or Without Carboplatin in Subjects With Ovarian Cancer
NCT06211023 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
Erlotinib Plus Carboplatin and Paclitaxel in Ovarian Carcinoma
NCT00059787 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Fluzoparib Combined With QL1101 Maintenance Treatment in Patients With Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy
NCT05585281 ·Status: RECRUITING ·Phase: PHASE2
-
Study of AMG 386 in Combination With Paclitaxel and Carboplatin in Subjects With Ovarian Cancer
NCT01253681 ·Status: COMPLETED ·Phase: PHASE1