Trial Outcomes & Findings for Executive Functioning Training Study (NCT NCT05598047)

Participants were recruited from our university HIV/AIDS clinic. They were screened over the phone to ascertain if they met some basic entry criteria (i.e., had HIV, living within 60 miles from the center, not homeless, no significant neuromedical comorbidities, not legally blind/deaf, not currently undergoing radiation or chemotherapy, no history of severe head trauma). Participants were compensated for their time. Recruitment occurred from 6/14/2023 to 2/14/2025.

Executive Functioning Training Study

Participants rated whether they need computerize cognitive training to improve their cognition (scale from 0=not at all to 10=extremely).

Participants were asked how much they enjoyed the cognitive training (scale from 1=not at all to 5=extremely).

Investigators administer a qualitative (i.e., open-ended responses) survey to assess what participants liked/disliked (i.e. preferences) about the training and how to improve it. These verbal responses were then coded into categories for those who were assigned to the EFT group.

Investigators calculated the hours of training completed. Ranges will be from 0 to 20 hours (i.e., 0% to 100%).

Investigators calculated the attrition rate of the protocol as measured by those who completed a posttest assessment; this was the indicator that participants completed the study.

Cognitive Inconsistency (a type of cognitive intra-individual variability) was calculated with Variability (measures consistency of participants hit reaction times during the test) and Hit Rate Standard Deviation (measures consistency of response speed). These are measured in T scores; 50 indicates a population mean with a standard deviation of 10. Higher T scores indicate more inconsistency, which is considered a poorer cognitive indicator. There is no clinically relevant threshold.