Impact of Deep Neuromuscular Blockade During Total Hip Replacement Surgery on Postoperative Recovery and Immune Function
NCT05562999 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2024-09-19
Summary
Monocenter randomized controlled trial to compare the effect of deep neuromuscular blockade (NMB) versus moderate NMB during total hip replacement surgery on postoperative quality of recovery and innate immune function.
Conditions
- Neuromuscular Blockade
- Innate Inflammatory Response
- Quality of Life
- Postoperative Complications
Interventions
- DRUG
-
Rocuronium Bromide
Moderate NMB (TOF 1-2)
- DRUG
-
Rocuronium Bromide
Deep NMB (PTC 1-2)
Sponsors & Collaborators
- collaborator INDUSTRY
-
Radboud University Medical Center
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-11-18
- Primary Completion
- 2024-08-29
- Completion
- 2024-08-29
Countries
- Netherlands
Study Locations
More Related Trials
-
Fascia Iliaca Compartment Blocks for Pain Control in Hip Fractures
NCT04086914 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
The Analgesic Efficacy of Pericapsular Nerve Group (PENG) Block in Patients Undergoing Primary Total Hip Arthoplasty:
NCT06557044 ·Status: RECRUITING ·Phase: NA
-
Suprainguinal Fascia Iliaca Compartment Block in Direct Anterior Approach to Total Hip Arthroplasty
NCT05237479 ·Status: WITHDRAWN ·Phase: NA
-
Adductor Canal Block and Recovery After Total Knee Replacement Surgery
NCT02411149 ·Status: COMPLETED ·Phase: PHASE4
-
Hip Scope Fascia-iliaca (FI) Block Study
NCT02365961 ·Status: COMPLETED ·Phase: PHASE4
-
Pericapsular Nerve Group Block for Positional Pain and Postoperative Analgesia in Hip Fractures
NCT05079087 ·Status: UNKNOWN ·Phase: NA
-
Comparison of Continuous Femoral Nerve Block and Adductor Canal Block After Total Knee Replacement Therapy
NCT02125903 ·Status: COMPLETED ·Phase: NA
-
Adductor Canal Blockade vs Femoral Nerve Blockade on Muscle Strength, Mobility and Pain After TKA
NCT01922596 ·Status: COMPLETED ·Phase: PHASE4
-
Patients With Acute Hip Fractures Will Receive Either the PENG Block or no Block Respectively.
NCT04996979 ·Status: UNKNOWN ·Phase: NA
-
Comparison Of Deep Versus Moderate Neuromuscular Blockade on Intra-Operative Blood Loss During Spinal Surgery
NCT05294926 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip Fracture
NCT03226080 ·Status: WITHDRAWN ·Phase: PHASE4
-
Adductor Canal Vs Adductor Canal Plus SPANK Block for Postoperative Pain in Knee Arthroplasty Surgery
NCT04290442 ·Status: WITHDRAWN ·Phase: PHASE4
-
Pericapsular Nerve Group Block: An Imaging Study for Determination of the Spread of the Injectate Using 3-D CT Scan
NCT06062134 ·Status: COMPLETED ·Phase: NA
-
Fascia Iliaca Compartment Block For Analgesia After Total Hip Arthroplasty
NCT01758497 ·Status: COMPLETED ·Phase: NA
-
Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty
NCT02658149 ·Status: COMPLETED ·Phase: PHASE4
-
Motor-Sparing Peripheral Nerve Blockade Facilitates Mobility Post Total Knee Arthroplasty: A Randomized Controlled Trial
NCT02773537 ·Status: COMPLETED ·Phase: NA
-
Effectiveness of PENG Block Combined to LFCN Block on the Quality of Recovery After Total Hip Replacement
NCT04245280 ·Status: COMPLETED ·Phase: NA
-
Effect of Deep Versus Moderate Neuromuscular Block During Sevoflurane Anesthesia on Intraoperative Surgical Conditions.
NCT03170661 ·Status: COMPLETED ·Phase: PHASE4
-
Regional Anesthesia in Hip Arthroscopy
NCT02674113 ·Status: WITHDRAWN ·Phase: NA
-
Does Limb Pre-Conditioning Reduce Pain After Hip Arthroscopy
NCT04925791 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Hematoma Block on Postoperative Pain After Femoral Intramedullary Rodding: A Randomized Trial
NCT04860856 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Ropivacaine Combined With Different Concentrations of Methylene Blue Fascia Iliaca Block in Postoperative Analgesia, Cognition, and Hip Function Recovery in Patients Undergoing Hip Arthroplasty
NCT06520306 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Trial Comparing Impact of PENG Block on Quality of Recovery Compared to No-block for Primary Total Hip Arthroplasty
NCT04591353 ·Status: COMPLETED ·Phase: PHASE3
-
Ultrasound-guided Femoral Nerve Blocks in Elderly Patients With Hip Fractures
NCT01701414 ·Status: COMPLETED ·Phase: PHASE2
-
Pericapsular Nerve Group (PENG) Block Combined With Periarticular Multimodal Drug Injection (PMDI) Versus Isolated PMDI for Pain Management After Total Hip Arthroplasty: a Randomized Controlled Trial
NCT05320913 ·Status: UNKNOWN ·Phase: NA