Virtual Reality Exposure and Respiratory Relaxation-Based Coping With Cocaine Craving in Cocaine Users

Summary

Our study main objective is to test whether virtual reality exposure could elicit cocaine craving and its physiological arousal in cocaine users. Investigators aim to compare self-reported cocaine craving, self-efficacy to cope with craving and emotional states levels in 11 voluntary and adults cocaine users in 3 consecutive 10-mins conditions: Neutral VR (virtual reality exposure to neutral stimuli), Cocaine VR (virtual reality exposure to cocaine use-related stimuli) and Relaxation (respiratory relaxation).

Conditions

• Virtual Reality Exposure Therapy
• Cocaine Use Disorder

Interventions

DEVICE

Virtual Reality Exposure to Neutral Cues

Virtual reality exposure to neutral stimuli (360 degrees visual and audio immersion with Oculus Quest 2 virtual reality headset). Participants stay sitted on chair and can tilt, rotate and move forward and backward upper body members. No interaction with the investigator during the virtual reality immersion.

BEHAVIORAL

Respiratory Relaxation

Respiratory relaxation practise. No interaction with the investigator during the relaxation practise.

DEVICE

Virtual Reality Exposure to Cocaine-Related Cues

Virtual reality exposure to cocaine-related stimuli (360 degrees visual and audio immersion with Oculus Quest 2 virtual reality headset). Participants stay sitted on chair and can tilt, rotate and move forward and backward upper body members. No interaction with the investigator during the virtual reality immersion.

Sponsors & Collaborators

• ICube Laboratory - Team IGG

  collaborator UNKNOWN

• Ithaque Association

  collaborator UNKNOWN

• University Hospitals of Strasbourg

  collaborator UNKNOWN

• University Hospital, Strasbourg, France

  collaborator OTHER

• The French National Cancer Institute

  collaborator UNKNOWN

• The French Institute for Public Health Research

  collaborator UNKNOWN

• Laboratoire de Psychologie des Cognitions

  lead OTHER

Principal Investigators

• Thomas Lehoux, Ph.D. Candidate · Laboratoire de Psychologie des Cognitions (Strasbourg University)

Study Design

Allocation

NON_RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2021-03-31

Primary Completion

2021-07-29

Completion

2021-07-29

Countries

• France

Study Locations