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The Validation and Development of Termination-of-Resuscitation (TOR) Rules in OHCA Patients in Asia Countries

NCT05545176 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 140000

Last updated 2026-02-25

No results posted yet for this study

Summary

Objectives/Hypotheses

1. Prehospital termination-of-resuscitation (TOR) rules were developed in North American and European sites. Whether they remained valid in different geographic, ethnic, and cultural background areas is still under debate.
2. Differences in characteristics of out-of-hospital cardiac arrests (OHCAs) and configurations of emergency medical service (EMS) between the Western and Asian countries, including relatively lower rate of presenting shockable rhythm (i.e. ventricular fibrillation / ventricular tachycardia; VF/VT), lower rates of bystander CPR, less advanced life support (ALS) implementation, and less public access defibrillators, might create potential threats to the prediction accuracy of TOR rules.
3. We aim to conduct a study to validate the performance of ever published TOR rules in Asian OHCA population, including non-traumatic, traumatic, and pediatric OHCA patients. Furthermore, assess the possible variables that may impact the performance of TOR rules.
4. We also aim to develop new TOR rules based on PAROS registry for Asia population, focusing on non-traumatic, traumatic, and pediatric OHCA patients, respectively.

Conditions

  • Out-Of-Hospital Cardiac Arrest

Interventions

OTHER

termination of resuscitation rules

Use retrospective data to analyze the accuracy termination of resuscitation rules and further develope a termination of resuscitation rule.

Sponsors & Collaborators

  • Singapore Clinical Research Institute

    collaborator OTHER

  • National Taiwan University Hospital

    lead OTHER

Principal Investigators

  • Shu-Hsien Hsu, MPH · National Taiwan University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-01-01
Primary Completion
2032-06-01
Completion
2032-12-31

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05545176 on ClinicalTrials.gov