A Study Assessing KB407 for the Treatment of Cystic Fibrosis
NCT05504837 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2026-05-07
Summary
This study will evaluate safety and tolerability of ascending doses of nebulized KB407 in adults with cystic fibrosis.
Conditions
Interventions
- BIOLOGICAL
-
KB407 (Nebulization)
Nebulized solution of KB407, a replication-defective HSV-1 expressing full length human CFTR
Sponsors & Collaborators
-
Krystal Biotech, Inc.
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-06-30
- Primary Completion
- 2026-12-31
- Completion
- 2027-03-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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