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Repetitive Transcranial Magnetic Stimulation in SCA3 Patients

NCT05502432 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 39

Last updated 2022-08-16

No results posted yet for this study

Summary

Machado-Joseph Disease (MJD) or spinocerebellar ataxia type 3 (SCA3) is the most common spinocerebellar ataxia worldwide.Repetitive transcranial magnetic stimulation (rTMS) is a form of brain stimulation therapy used to treat depression and cerebellar ataxias. In this randomized, double-blind, sham-controlled study, the investigators will evaluate whether a 15 day treatment with 1 Hz of repetitive transcranial magnetic stimulation (rTMS) can improve symptoms (motor symptoms and non-motor symptoms) in patients with MJD.

Conditions

  • Spinocerebellar Ataxia Type 3

Interventions

DEVICE

Active repetitive transcranial magnetic stimulation

Consecutive 15-day active treatment with 1 Hz of repetitive transcranial magnetic stimulation

DEVICE

Sham repetitive transcranial magnetic stimulation

Consecutive 15-day sham treatment with 1 Hz of repetitive transcranial magnetic stimulation

Sponsors & Collaborators

  • Ning Wang, MD., PhD.

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-12-17
Primary Completion
2019-10-01
Completion
2019-10-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05502432 on ClinicalTrials.gov