Trial Outcomes & Findings for Title: Leveraging Technology to Address Health Outcomes of Cancer Survivors (NCT NCT05499663)
NCT ID: NCT05499663
Last Updated: 2026-02-06
Results Overview
Number of participants who logged data at least three times in the POSTHOC app
Recruitment status
COMPLETED
Study phase
PHASE1/PHASE2
Target enrollment
51 participants
Primary outcome timeframe
12 weeks
Results posted on
2026-02-06
Participant Flow
Completion of baseline assessments was necessary before randomization
Participant milestones
| Measure |
POSTHOC App
The POSTHOC app is a smartphone application that will deliver the Survivorship Care Plan and promote healthy lifestyle behaviors consistent with the individual's Care Plan
|
Control
Usual care
|
|---|---|---|
|
Overall Study
STARTED
|
23
|
11
|
|
Overall Study
COMPLETED
|
22
|
10
|
|
Overall Study
NOT COMPLETED
|
1
|
1
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Title: Leveraging Technology to Address Health Outcomes of Cancer Survivors
Baseline characteristics by cohort
| Measure |
POSTHOC App
n=23 Participants
The POSTHOC app is a smartphone application that will deliver the Survivorship Care Plan and promote healthy lifestyle behaviors consistent with the individual's Care Plan
|
Control
n=11 Participants
Usual care
|
Total
n=34 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Continuous
|
63.5 years
STANDARD_DEVIATION 10.2 • n=41 Participants
|
57.5 years
STANDARD_DEVIATION 13.6 • n=1581 Participants
|
61.6 years
STANDARD_DEVIATION 11.6 • n=4626 Participants
|
|
Sex: Female, Male
Female
|
19 Participants
n=41 Participants
|
8 Participants
n=1581 Participants
|
27 Participants
n=4626 Participants
|
|
Sex: Female, Male
Male
|
4 Participants
n=41 Participants
|
3 Participants
n=1581 Participants
|
7 Participants
n=4626 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
0 Participants
n=41 Participants
|
0 Participants
n=1581 Participants
|
0 Participants
n=4626 Participants
|
|
Race (NIH/OMB)
Asian
|
0 Participants
n=41 Participants
|
0 Participants
n=1581 Participants
|
0 Participants
n=4626 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=41 Participants
|
0 Participants
n=1581 Participants
|
0 Participants
n=4626 Participants
|
|
Race (NIH/OMB)
Black or African American
|
3 Participants
n=41 Participants
|
1 Participants
n=1581 Participants
|
4 Participants
n=4626 Participants
|
|
Race (NIH/OMB)
White
|
20 Participants
n=41 Participants
|
10 Participants
n=1581 Participants
|
30 Participants
n=4626 Participants
|
|
Race (NIH/OMB)
More than one race
|
0 Participants
n=41 Participants
|
0 Participants
n=1581 Participants
|
0 Participants
n=4626 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=41 Participants
|
0 Participants
n=1581 Participants
|
0 Participants
n=4626 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
0 Participants
n=41 Participants
|
0 Participants
n=1581 Participants
|
0 Participants
n=4626 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
23 Participants
n=41 Participants
|
11 Participants
n=1581 Participants
|
34 Participants
n=4626 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=41 Participants
|
0 Participants
n=1581 Participants
|
0 Participants
n=4626 Participants
|
PRIMARY outcome
Timeframe: 12 weeksNumber of participants who logged data at least three times in the POSTHOC app
Outcome measures
| Measure |
POSTHOC App
n=23 Participants
The POSTHOC app is a smartphone application that will deliver the Survivorship Care Plan and promote healthy lifestyle behaviors consistent with the individual's Care Plan. These participants will have access to the following features of the POSTHOC app: their individualized Survivorship Care Plan, recommendations for daily step count and a comparison of their actual (via Fitbit) vs. their goal, recommendations for daily food groups and a comparison to their actual (entered manually) to their goal, symptom logging, and Ecological Momentary Assessment
|
Control
n=11 Participants
Usual care. These participants downloaded the POSTHOC app, but only had access to the Ecological Momentary Assessment feature of the app.
|
|---|---|---|
|
Number of Participants Who Logged Data at Least Three Times in the POSTHOC App
|
12 Participants
|
1 Participants
|
PRIMARY outcome
Timeframe: 6 weeks7-point Likert scale for usefulness flanked by 1=not at all useful and 7=extremely useful
Outcome measures
| Measure |
POSTHOC App
n=18 Participants
The POSTHOC app is a smartphone application that will deliver the Survivorship Care Plan and promote healthy lifestyle behaviors consistent with the individual's Care Plan. These participants will have access to the following features of the POSTHOC app: their individualized Survivorship Care Plan, recommendations for daily step count and a comparison of their actual (via Fitbit) vs. their goal, recommendations for daily food groups and a comparison to their actual (entered manually) to their goal, symptom logging, and Ecological Momentary Assessment
|
Control
Usual care. These participants downloaded the POSTHOC app, but only had access to the Ecological Momentary Assessment feature of the app.
|
|---|---|---|
|
Usefulness of POSTHOC App
|
3.4 points
Standard Deviation 2.0
|
—
|
PRIMARY outcome
Timeframe: 12 weeks7-point Likert scale for usefulness flanked by 1=not at all useful and 7=extremely useful
Outcome measures
| Measure |
POSTHOC App
n=19 Participants
The POSTHOC app is a smartphone application that will deliver the Survivorship Care Plan and promote healthy lifestyle behaviors consistent with the individual's Care Plan. These participants will have access to the following features of the POSTHOC app: their individualized Survivorship Care Plan, recommendations for daily step count and a comparison of their actual (via Fitbit) vs. their goal, recommendations for daily food groups and a comparison to their actual (entered manually) to their goal, symptom logging, and Ecological Momentary Assessment
|
Control
Usual care. These participants downloaded the POSTHOC app, but only had access to the Ecological Momentary Assessment feature of the app.
|
|---|---|---|
|
Usefulness of POSTHOC App
|
4.3 points
Standard Deviation 2.3
|
—
|
PRIMARY outcome
Timeframe: 6 weeks7-point Likert scale flanked by 1=not at all likely to recommend to others and 7=extremely likely
Outcome measures
| Measure |
POSTHOC App
n=18 Participants
The POSTHOC app is a smartphone application that will deliver the Survivorship Care Plan and promote healthy lifestyle behaviors consistent with the individual's Care Plan. These participants will have access to the following features of the POSTHOC app: their individualized Survivorship Care Plan, recommendations for daily step count and a comparison of their actual (via Fitbit) vs. their goal, recommendations for daily food groups and a comparison to their actual (entered manually) to their goal, symptom logging, and Ecological Momentary Assessment
|
Control
Usual care. These participants downloaded the POSTHOC app, but only had access to the Ecological Momentary Assessment feature of the app.
|
|---|---|---|
|
Likely to Recommend the POSTHOC App
|
4.2 points
Standard Deviation 2.2
|
—
|
PRIMARY outcome
Timeframe: 12 weeks7-point Likert scale flanked by 1=not at all likely to recommend to others and 7=extremely likely
Outcome measures
| Measure |
POSTHOC App
n=19 Participants
The POSTHOC app is a smartphone application that will deliver the Survivorship Care Plan and promote healthy lifestyle behaviors consistent with the individual's Care Plan. These participants will have access to the following features of the POSTHOC app: their individualized Survivorship Care Plan, recommendations for daily step count and a comparison of their actual (via Fitbit) vs. their goal, recommendations for daily food groups and a comparison to their actual (entered manually) to their goal, symptom logging, and Ecological Momentary Assessment
|
Control
Usual care. These participants downloaded the POSTHOC app, but only had access to the Ecological Momentary Assessment feature of the app.
|
|---|---|---|
|
Likely to Recommend the POSTHOC App
|
4.4 points
Standard Deviation 2.3
|
—
|
SECONDARY outcome
Timeframe: 6 weeksThis is a sum of severities of the core patient-reported symptoms from the MD Anderson Symptom Inventory, including fatigue, insomnia, pain, appetite loss, dyspnea (shortness of breath), cognitive problems, nausea, distress, and sensory neuropathy. The scale ranges from 0-130. A higher score indicates higher symptom burden.
Outcome measures
| Measure |
POSTHOC App
n=21 Participants
The POSTHOC app is a smartphone application that will deliver the Survivorship Care Plan and promote healthy lifestyle behaviors consistent with the individual's Care Plan. These participants will have access to the following features of the POSTHOC app: their individualized Survivorship Care Plan, recommendations for daily step count and a comparison of their actual (via Fitbit) vs. their goal, recommendations for daily food groups and a comparison to their actual (entered manually) to their goal, symptom logging, and Ecological Momentary Assessment
|
Control
n=9 Participants
Usual care. These participants downloaded the POSTHOC app, but only had access to the Ecological Momentary Assessment feature of the app.
|
|---|---|---|
|
Cumulative Symptom Burden
|
20.0 points
Standard Deviation 20.8
|
18.6 points
Standard Deviation 18.3
|
SECONDARY outcome
Timeframe: 12 weeksThis is a sum of severities of the core patient-reported symptoms from the MD Anderson Symptom Inventory, including fatigue, insomnia, pain, appetite loss, dyspnea (shortness of breath), cognitive problems, nausea, distress, and sensory neuropathy. The scale ranges from 0-130. A higher score indicates higher symptom burden.
Outcome measures
| Measure |
POSTHOC App
n=21 Participants
The POSTHOC app is a smartphone application that will deliver the Survivorship Care Plan and promote healthy lifestyle behaviors consistent with the individual's Care Plan. These participants will have access to the following features of the POSTHOC app: their individualized Survivorship Care Plan, recommendations for daily step count and a comparison of their actual (via Fitbit) vs. their goal, recommendations for daily food groups and a comparison to their actual (entered manually) to their goal, symptom logging, and Ecological Momentary Assessment
|
Control
n=9 Participants
Usual care. These participants downloaded the POSTHOC app, but only had access to the Ecological Momentary Assessment feature of the app.
|
|---|---|---|
|
Cumulative Symptom Burden
|
19.8 points
Standard Deviation 21.4
|
26.7 points
Standard Deviation 21.7
|
Adverse Events
POSTHOC App
Serious events: 1 serious events
Other events: 0 other events
Deaths: 0 deaths
Control
Serious events: 0 serious events
Other events: 1 other events
Deaths: 0 deaths
Before Randomization
Serious events: 1 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
| Measure |
POSTHOC App
n=23 participants at risk
The POSTHOC app is a smartphone application that will deliver the Survivorship Care Plan and promote healthy lifestyle behaviors consistent with the individual's Care Plan
|
Control
n=11 participants at risk
Usual care
|
Before Randomization
n=17 participants at risk
Participants who consented to the study but then withdrew before randomization
|
|---|---|---|---|
|
Nervous system disorders
Cancer metastasis
|
0.00%
0/23 • From enrollment to the end of 12 weeks
|
0.00%
0/11 • From enrollment to the end of 12 weeks
|
5.9%
1/17 • From enrollment to the end of 12 weeks
|
|
Respiratory, thoracic and mediastinal disorders
Pneumonia
|
4.3%
1/23 • From enrollment to the end of 12 weeks
|
0.00%
0/11 • From enrollment to the end of 12 weeks
|
0.00%
0/17 • From enrollment to the end of 12 weeks
|
Other adverse events
| Measure |
POSTHOC App
n=23 participants at risk
The POSTHOC app is a smartphone application that will deliver the Survivorship Care Plan and promote healthy lifestyle behaviors consistent with the individual's Care Plan
|
Control
n=11 participants at risk
Usual care
|
Before Randomization
n=17 participants at risk
Participants who consented to the study but then withdrew before randomization
|
|---|---|---|---|
|
Musculoskeletal and connective tissue disorders
Back pain
|
0.00%
0/23 • From enrollment to the end of 12 weeks
|
9.1%
1/11 • From enrollment to the end of 12 weeks
|
0.00%
0/17 • From enrollment to the end of 12 weeks
|
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place