MedTrace Logo

MiECC Versus Conventional Cardiopulmonary Bypass in Cardiac Surgery (MiECS)

NCT05487612 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1300

Last updated 2026-03-30

No results posted yet for this study

Summary

MiECS is one of the largest multicentre randomised controlled trials on extracorporeal circulation conducted under the auspices of Minimal Invasive Extracorporeal Technologies International Society (MiECTiS). It is designed to ultimately address the emerging effectiveness of MiECC systems in the light of modern perfusion practice worldwide. The primary hypothesis is that MiECC, as compared to conventional CPB (cCPB), reduces the proportion of patients experiencing serious perfusion-related postoperative morbidity after cardiac surgery. The study will be led by the Clinical Research Unit of the Special Unit for Biomedical Research and Education (SUBRE), Aristotle University of Thessaloniki School of Medicine in Greece (AUSoM) with Chief Investigator Professor Kyriakos Anastasiadis, who is a key-opinion-leader in the field of MiECC, founder and Executive Board of MiECTiS.

Conditions

Interventions

DEVICE

Minimal Invasive Extracorporeal Circulation

Cardiac surgery with Minimal Invasive Extracorporeal Circulation (MiECC).

DEVICE

Conventional cardiopulmonary bypass

Cardiac surgery with conventional cardiopulmonary bypass (cCPB).

Sponsors & Collaborators

  • Minimal Invasive Extracorporeal Technologies International Society (MiECTiS)

    collaborator UNKNOWN

  • Aristotle University Of Thessaloniki

    lead OTHER

Principal Investigators

  • Kyriakos Anastasiadis, Professor · Aristotle University Of Thessaloniki

  • Polychronis Antonitsis, Assoc. Prof. · Aristotle University Of Thessaloniki

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-05-26
Primary Completion
2028-12-31
Completion
2029-03-31

Countries

  • Canada
  • Germany
  • Greece
  • Italy
  • Turkey (Türkiye)
  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05487612 on ClinicalTrials.gov