Surufatinib Combined With TAS-102 in Third-line and Later-line Therapy of Patients With Advanced Pancreatic Cancer
NCT05481463 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 22
Last updated 2025-05-28
Summary
This is a single-center, single-arm, open-label, phase 2 clinical study, to explore the efficacy and safety of surufatinib combined with TAS-102 in third-line and later-line therapy of patients with advanced pancreatic cancer
Conditions
- Pancreatic Neoplasms
Interventions
- DRUG
-
Surufatinib
surufatinib,250mg, qd, po, 28 days for a cycle
- DRUG
-
TAS-102
TAS-102,35mg/m2, po, d1-5, d8-12, bid, 28 days for a cycle
Sponsors & Collaborators
-
Sun Yat-sen University
lead OTHER
Principal Investigators
-
Dongsheng Zhang, PhD · Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-01-30
- Primary Completion
- 2025-03-31
- Completion
- 2025-05-10
Countries
- China
Study Locations
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