Triage of Advanced Cervical Cancer Through Immunotherapy Induction (TRACTION)
NCT05475171 · Status: SUSPENDED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 47
Last updated 2026-05-22
Summary
To learn if MGD019 can help to control cervical cancer in patients who have yet to receive treatment.
Conditions
Interventions
- DRUG
-
Lorigerlimab
Given by vein (IV)
Sponsors & Collaborators
- collaborator INDUSTRY
-
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Amir Jazeri, MD · M.D. Anderson Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-12-13
- Primary Completion
- 2026-06-30
- Completion
- 2026-06-30
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Proton Therapy for Locally Advanced Cervical Cancer
NCT06462378 ·Status: RECRUITING ·Phase: PHASE2
-
A Multicenter, Prospective, Randomized Trial of Adjuvant Chemotherapy for Early-Stage Cervical Cancer Patients
NCT01755897 ·Status: COMPLETED ·Phase: NA
-
Mapatumumab, Cisplatin and Radiotherapy for Advanced Cervical Cancer
NCT01088347 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Randomized Study of Z-100 Plus Radiation Therapy to Treat Cervical Cancer
NCT02247232 ·Status: COMPLETED ·Phase: PHASE3
-
Biomarker-Driven Radiation Therapy Dose Reduction After Transoral Robotic Surgery for the Treatment of HPV-Positive Oropharyngeal Cancer
NCT05387915 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Cetuximab, Cisplatin, and Radiotherapy in Women With Locally Advanced Cervical Carcinoma
NCT00292955 ·Status: UNKNOWN ·Phase: PHASE2
-
Single Application Brachytherapy in Cervical Cancer
NCT03110497 ·Status: UNKNOWN ·Phase: NA
-
Radiation Therapy and Chemotherapy in Treating Patients With Locally Advanced Cervical Cancer
NCT00054444 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase II Study of Neoadjuvant Sacituzumab Tirumotecan in Combination With Iparomlimab and Tuvonralimab in Locally Advanced Cervical Cancer
NCT07348861 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Phase Ib Trial of Multivalent Autophagosome Vaccine With or Without GITR Agonist, With Anti-PD-1 Immunotherapy in HNSCC
NCT04470024 ·Status: RECRUITING ·Phase: PHASE1
-
TSR-042 as Maintenance Therapy for Patients With High-risk Locally Advanced Cervical Cancer After Chemo-radiation
NCT03833479 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Anlotinib Combined With Concurrent Chemoradiotherapy in the Treatment of Locally Advanced Cervical Cancer
NCT05772377 ·Status: UNKNOWN ·Phase: PHASE2
-
Systemic Consolidation Therapy After Chemoradiation Therapy Following Operation for High Risk Early Stage Cervical Cancer
NCT00592059 ·Status: UNKNOWN
-
Evaluation of TRANSKRIP ® Plus Chemotherapy in Recurrent-Persistent Cervical Cancer
NCT02446652 ·Status: WITHDRAWN ·Phase: PHASE3
-
Radiation Therapy With or Without Cetuximab in Treating Patients With Stage III or Stage IV Cancer of the Oropharynx, Hypopharynx, or Larynx
NCT00004227 ·Status: TERMINATED ·Phase: PHASE3
-
Pembrolizumab and Lenvatinib in Advanced Cervical Cancer
NCT04865887 ·Status: RECRUITING ·Phase: PHASE2
-
Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer
NCT05172245 ·Status: RECRUITING ·Phase: PHASE1
-
Radiation Therapy Plus Cisplatin and Gemcitabine in Treating Patients With Cervical Cancer
NCT00068549 ·Status: COMPLETED ·Phase: PHASE1
-
Intensity Modulated Radiation Therapy With Cisplatin and Gemcitabine to Treat Locally Advanced Cervical Carcinoma
NCT01554410 ·Status: COMPLETED ·Phase: PHASE1
-
Gefitinib in Treating Patients With Cervical Cancer
NCT00049556 ·Status: COMPLETED ·Phase: PHASE2
-
Tirapazamine, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer
NCT00098995 ·Status: COMPLETED ·Phase: PHASE1
-
Cisplatin and Radiation Therapy Followed by Paclitaxel and Carboplatin in Treating Patients With Stage IB-IVA Cervical Cancer
NCT01295502 ·Status: UNKNOWN ·Phase: PHASE1
-
Non-Invasive Cervical Cancer Radiotherapy for Stage IB-IVB
NCT03146039 ·Status: WITHDRAWN ·Phase: PHASE2
-
Systemic and Tumor Immune Response During Pelvic (Chemo)Radiation and/or Brachytherapy for Cervical Cancer
NCT06804135 ·Status: RECRUITING
-
Radiation Therapy With or Without Chemotherapy in Patients With Stage I-IIA Cervical Cancer Who Previously Underwent Surgery
NCT01101451 ·Status: COMPLETED ·Phase: PHASE3