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Complex Regional Pain Syndrome (CRPS) and the Gut-bacteria

NCT05473338 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2022-10-18

No results posted yet for this study

Summary

The purpose of this study is to investigate, for the first time, whether gut bacteria composition and function of patients with CRPS differ from those of healthy adults. Samples of stool, urine and blood will be collected from patients with CRPS and from healthy adults. The type and function of bacteria of CRPS patients will be analyzed and compared to those of healthy adults to test if potential differences could explain the mechanism/s involved with the development of CRPS.

Conditions

  • CRPS

Interventions

DIAGNOSTIC_TEST

Stool and blood samples

fecal microbiome and metabolomics, as well as metabolites in plasma

OTHER

Physical examination

physical examination performed by a physician to confirm CRPS diagnosis and assess patient's eligibility to participate in the study. The exam will include skin temperature measured using a laser/infrared skin thermometry.

OTHER

Questionnaires

Questionnaires measuring pain level, sleep, mood and diet parameters.

Sponsors & Collaborators

  • Louise and Alan Edwards Foundation

    collaborator UNKNOWN

  • Rambam Health Care Campus

    collaborator OTHER

  • McGill University Health Centre/Research Institute of the McGill University Health Centre

    lead OTHER

Principal Investigators

  • Yoram Shir, MD · McGill University Health Centre/Research Institute of the McGill University Health Centre

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-04-14
Primary Completion
2022-10-14
Completion
2024-06-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05473338 on ClinicalTrials.gov