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Neuromuscular Electrical Stimulation in Mechanically Ventilated Patients

NCT05465291 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2023-04-11

No results posted yet for this study

Summary

Intensive care unit-acquired muscle weakness (ICUAMW) is a common problem following an ICU admission and is associated with prolonged hospitalization, delayed weaning and increased mortality. Up to 25% of patients requiring mechanical ventilation (MV) for greater than 7 days develop ICUAW, and this figure may rise to 50-100% in the septic population. Long-term follow-up studies of survivors of critical illness have demonstrated significantly impaired health-related quality of life and physical functioning up to 5 years after ICU discharge, with weakness being the most commonly reported physical limitation. Early rehabilitation has been shown to be safe and feasible; however, commencement is often delayed due to a patient's inability to cooperate. An intervention that begins early in ICU admission without the need for patient volition may be beneficial in attenuating muscle wasting. Therefore, this study aims to evaluate the effect of neuromuscular electrical stimulation and early physical activity on ICU acquired muscle weakness in mechanically ventilated patient

Conditions

  • Neuromuscular Electrical Stimulation
  • ICU Acquired Muscle Weakness

Interventions

PROCEDURE

Exercise group

This group will receive passive/active range of motion (ROM) exercises. ROM exercises will include major muscle groups (i.e. biceps, triceps, and lower limbs) and will be applied from second day till seventh day of admission .

PROCEDURE

Neuromuscular Electrical Muscle Stimulation group

* Patients in NEMS group will receive neuromuscular electrical stimulation from second day till seventh day of admission. * Neuromuscular electrical stimulation will be implemented simultaneously on the rectus femoris, vastus lateralis, and vastus medialis muscles of both lower limbs, with two stimulators, in two 30-min sessions per day starting from the second day till seventh day of admission .

PROCEDURE

Neuromuscular Electrical Muscle Stimulation and Exercise group

Patients in this group will be subjected to Neuromuscular Electrical Muscle Stimulation and Exercise.

Sponsors & Collaborators

  • Damanhour University

    lead OTHER

Principal Investigators

  • Sahar Y Othman, Assit. Prof. · Faculty of Nursing, Damanhour University

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-18
Primary Completion
2023-02-18
Completion
2023-02-18

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05465291 on ClinicalTrials.gov