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Left Atrial Strain and Supraventricular Arrhythmia Burden in Cardiac Light Chain Amyloidosis Following Chemotherapy

NCT05448716 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2023-09-28

No results posted yet for this study

Summary

The purpose of this study to assess the longitudinal changes in left atrial strain and supraventricular arrhythmia burden after chemotherapeutic strategies in cardiac light chain amyloidosis.

Conditions

  • Supraventricular Arrhythmia
  • Left Atrial Abnormality
  • Amyloid Cardiomyopathy
  • Congestive Heart Failure

Interventions

DIAGNOSTIC_TEST

Left Atrial Strain Imaging

Two-dimensional, color Doppler, spectral Doppler recordings will be taken from parasternal, apical, subcostal, and modified sections using a Philips Epiq CVx echocardiography device and X5-1 probe. Conventional parameters, additional parameters, and strain analyzes will be performed with speckle tracking echocardiography from these recordings.

DIAGNOSTIC_TEST

Electrocardiography

Electrocardiography will be taken at baseline and the follow-up periods

Sponsors & Collaborators

  • Istanbul University - Cerrahpasa

    lead OTHER

Principal Investigators

  • Burçak Kılıçkıran Avcı, Assoc Prof. · Istanbul University - Cerrahpasa

  • Deniz Mutlu, MD · Istanbul University - Cerrahpasa

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-10
Primary Completion
2023-09-26
Completion
2023-10-30

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05448716 on ClinicalTrials.gov