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Serum Levels of Otolin-1 and Vitamin D in Pre- and Post-treatments of BPPV

NCT05446506 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 21

Last updated 2023-08-31

No results posted yet for this study

Summary

BPPV is the most common cause of vertigo. The pathophysiology of BPPV has not been cleared, several studies show that symptoms are caused by the displacement of otoconia from the macula of the utricle into the semicircular canals. These calcium carbonate particles then stimulate non-physiological movement of the endolymph leading to a false sensation of angular acceleration.

Biomarkers represent measurable products of biological processes, thus making an assessment of those processes more practical. Biomarkers in circulation are powerful indicators of normal and pathological biological processes, as well as, responses to pharmacological treatments. The inner ear-inclusive protein that has been published included Otolin-1, Otoconin-90/95, Prestin, Otoancorin, Otogelin, α-tectorin, β-tectorin and Cochlin.

Conditions

  • Benign Paroxysmal Positional Vertigo

Sponsors & Collaborators

  • Chiang Mai University

    lead OTHER

Principal Investigators

  • Suwicha Kaewsiri, MD · Department of Otolaryngology , Faculty of Medicine, Chiang Mai University

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-13
Primary Completion
2022-09-30
Completion
2023-02-28

Countries

  • Thailand

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05446506 on ClinicalTrials.gov