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The Impact of Exercise / Stress Stimuli on HMB Supplementation Efficacy

NCT05444959 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 130

Last updated 2025-10-02

No results posted yet for this study

Summary

The study aims at assessing the influence of β-hydroxy-β-methylbutyrate (HMB) free acid supplementation (90 mg/kg of fat free body mass/day) supplemented for 21 days on protein kinases activity and selected hormones levels, and subsequent improvements in muscle protein synthesis, lean body mass content and aerobic capacity.

Conditions

  • Supplementation
  • Sport
  • Sports Nutrition
  • Sports Dietetics
  • Protein Kinases
  • Aerobic Capacity
  • Fat Free Mass

Interventions

DIETARY_SUPPLEMENT

HMB supplementation

Group taking oral HMB free acid supplementation in a blinded liquid form.

DIETARY_SUPPLEMENT

Placebo treatment

Group taking oral supplementation with placebo (in a blinded liquid form).

Sponsors & Collaborators

  • National Science Centre, Poland

    collaborator OTHER_GOV

  • Faculty of Physical Education and Sport at Charles University, Czech Republic

    collaborator UNKNOWN

  • Poznan University of Life Sciences, Poland

    collaborator UNKNOWN

  • Poznan University of Medical Sciences

    collaborator OTHER

  • Poznan University of Physical Education

    lead OTHER

Principal Investigators

  • Krzysztof Durkalec-Michalski, Prof., PhD · Department of Sports Dietetics, Poznan University of Physical Education

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-09-10
Primary Completion
2024-12-20
Completion
2025-07-01

Countries

  • Czechia
  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05444959 on ClinicalTrials.gov