Lead-in Study of VGB-R04 Gene Therapy for Hemophilia B-- An Observational Survey Analysis Study
NCT05442528 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 20
Last updated 2022-07-05
Summary
This is a prospective, open, multicenter, observational lead-in study,to collect prospective efficacy and safety data of current replacement therapy in adult hemophilia B patients.
Conditions
- Hemophilia B
Sponsors & Collaborators
-
Shanghai Vitalgen BioPharma Co., Ltd.
lead INDUSTRY
Principal Investigators
-
Lei Zhang · Institute of Hematology & Blood Diseases Hospital, China
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-08-31
- Primary Completion
- 2024-12-31
- Completion
- 2024-12-31
More Related Trials
-
Evaluation of the Safety and Efficacy of Hemophilia B Gene Therapy Drug
NCT05203679 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
Lentiviral FIX Gene Therapy
NCT03961243 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of Recombinant AAV2/6 Human Factor 8 Gene Therapy SB-525 (PF-07055480) in Subjects With Severe Hemophilia A
NCT03061201 ·Status: COMPLETED ·Phase: PHASE2
-
Lentiviral FVIII Gene Therapy
NCT03217032 ·Status: RECRUITING ·Phase: PHASE1
-
A Study to Evaluate Prospective Efficacy and Safety Data of Current FIX Prophylaxis Replacement Therapy in Adult Hemophilia B Subjects (FIX:C≤2%) or Current FVIII Prophylaxis Replacement Therapy in Adult Hemophilia A Subjects (FVIII:C≤1%)
NCT03587116 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Safety and Efficacy of ZS801 in Adult Hemophilia B Patients
NCT05641610 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Long-Term Safety and Efficacy of Spark-Sponsored Gene Therapies in Males With Hemophilia A
NCT03432520 ·Status: ACTIVE_NOT_RECRUITING
-
Data Registry in Chinese Hemophilia A and B Patients
NCT07101224 ·Status: COMPLETED
-
A Gene Therapy Study for Hemophilia B
NCT02484092 ·Status: COMPLETED ·Phase: PHASE2
-
The Efficacy and Safety of ZS801 in Chinese Hemophilia B Patients.
NCT05630651 ·Status: RECRUITING ·Phase: NA
-
The Efficacy and Safety of ZS802 in Chinese Hemophilia A Patients.
NCT05523128 ·Status: RECRUITING ·Phase: NA
-
A Study of FVIII Gene Therapy for Hemophilia A
NCT05454774 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Gene Therapy for Chinese Hemophilia A
NCT04728841 ·Status: RECRUITING ·Phase: NA
-
Safety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophilia A or B Respectively
NCT05568719 ·Status: RECRUITING ·Phase: PHASE3
-
Long Term Follow-up (LTFU) of Subjects Who Received SB-318, SB-913, or SB-FIX
NCT04628871 ·Status: ACTIVE_NOT_RECRUITING
-
Safety and Efficacy Study of NGGT003 in Hemophilia A Patients
NCT06238908 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Comparison of Efficacy, Safety and Costs of Recombinant FVIII Products Between On-demand and Secondary Prophylaxis Groups in Haemophilia A Patients
NCT01817868 ·Status: COMPLETED
-
A Study to Evaluate the Efficacy and Safety of Factor IX Gene Therapy With PF-06838435 in Adult Males With Moderately Severe to Severe Hemophilia B
NCT03861273 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A
NCT07226206 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Study to Evaluate the Efficacy and Safety of PF-07055480 / Giroctocogene Fitelparvovec Gene Therapy in Moderately Severe to Severe Hemophilia A Adults
NCT04370054 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
To Evaluate the Clinical Study of GS1191-0445 Injection in the Treatment of Hemophilia A
NCT06833983 ·Status: RECRUITING ·Phase: PHASE3
-
Retrospective Study in Chinese Pediatric Hemophilia A Patients With rFⅧ Contained Regular Prophylaxis
NCT02263066 ·Status: COMPLETED
-
A Trial to Compare Prophylaxis Therapy to On-demand Therapy With a New Full Length Recombinant FVIII in Patients With Severe Hemophilia A
NCT01233258 ·Status: COMPLETED ·Phase: PHASE3
-
Long-term Safety and Efficacy Study and Dose-Escalation Substudy of PF 06838435 in Individuals With Hemophilia B
NCT03307980 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Liver Biopsy Following Gene Therapy For Hemophilia
NCT05932914 ·Status: NOT_YET_RECRUITING