Second-line Pharmacotherapy Patterns and Outcomes of Advanced Gastrointestinal Stromal Tumor: A Real-world Study
NCT05440357 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2025-02-26
Summary
This is a prospective, multicenter, observational real-world study to explore the second-line Pharmacotherapy patterns and clinical outcomes in GIST patients who progressed on or were intolerant to first-line anticancer treatment.
Conditions
Sponsors & Collaborators
-
Guangdong Provincial People's Hospital
collaborator OTHER -
Nanfang Hospital, Southern Medical University
collaborator OTHER -
Sixth Affiliated Hospital, Sun Yat-sen University
collaborator OTHER -
Peking University Shenzhen Hospital
collaborator OTHER -
Cancer Hospital of Guangxi Medical University
collaborator OTHER -
Hainan Cancer Hospital
collaborator OTHER -
The First Affiliated Hospital of Nanchang University
collaborator OTHER -
Second Affiliated Hospital of Nanchang University
collaborator OTHER -
Yunnan Cancer Hospital
collaborator OTHER -
Chongqing University Cancer Hospital
collaborator OTHER -
Xinhua Zhang, MD
lead OTHER
Principal Investigators
-
zhang xinhua, PhD · First affiliated hosptial,Sun Yat-sen university
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-07-01
- Primary Completion
- 2025-09-30
- Completion
- 2025-09-30
Countries
- China
Study Locations
More Related Trials
-
A Non-Interventional Study of Treatment Pattern and Clinical Outcomes in Chinese Participants With Gastric Cancer
NCT01839500 ·Status: COMPLETED
-
Postoperative Sequence Chemoradiotherapy Compared With Chemotherapy Alone for Advanced Gastric Cancer
NCT01197118 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy and Safety of Anlotinib in Patients With Advanced Gastrointestinal Stromal Tumor After Failure of Imatinib: a Prospective, Single Arm and Multicenter Trial
NCT04106024 ·Status: UNKNOWN ·Phase: PHASE2
-
Ripretinib Used for Resectable Metastatic GIST After Failure of Imatinib Therapy
NCT05132738 ·Status: UNKNOWN ·Phase: NA
-
Irinotecan and Cisplatin for High Grade Neuroendocrine Carcinoma of the Gastrointestinal Tract
NCT00353015 ·Status: COMPLETED ·Phase: PHASE2
-
Pegliposomal Doxorubicin and 5-fluorouracil as Second Line Therapy for Metastatic Gastric Cancer
NCT04358341 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoadjuvant Chemoradiotherapy vs. Chemotherapy Followed by Radical Gastrectomy and Adjuvant Chemotherapy for Advanced Gastric Cancer
NCT01815853 ·Status: COMPLETED ·Phase: PHASE3
-
Compare S-1 for 6 Months to 1 Year as Adjuvant Chemotherapy After D2 Resection in Patients With Gastric Cancer Staged II , IIIA or IIIB.
NCT02736552 ·Status: WITHDRAWN ·Phase: PHASE3
-
Real World Study of Immune Checkpoint Inhibitors for Advanced Gastric Cancer
NCT04086888 ·Status: UNKNOWN
-
A Phase 2 Trial of Optimizing Platinum-Based Chemotherapy Based on ERCC1 Expression as First-Line Treatment in Patients With Locally Advanced or Metastatic Gastric Cancer
NCT01967875 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase I Study of S-1 in Combination With Radiotherapy in Locally Advanced or Recurrent Gastric Cancer
NCT01291407 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess DCC-2618 and Sunitinib in Patients With Advanced GIST After Treatment With Imatinib
NCT04633122 ·Status: COMPLETED ·Phase: PHASE2
-
Camrelizumab Combined With Apatinib Mesylate Tablets and Nab-paclitaxel in the Second-line Treatment of Advanced Gastric Cancer
NCT04572542 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Triplet Combination of Cytotoxics as First-line Treatment for Metastatic Gastric Cancer
NCT04358354 ·Status: UNKNOWN ·Phase: PHASE3
-
A Trail of CDK4 / 6 Inhibitor and MEK Inhibitor in the Treatment of Metastatic Digestive System Tumors
NCT04615312 ·Status: UNKNOWN ·Phase: PHASE1
-
Albumin Bound Paclitaxel Plus S-1 as the First Line Chemotherapy in Advanced or Recurrent Gastric Cancer
NCT02229058 ·Status: COMPLETED ·Phase: PHASE2
-
Trastuzumab Plus Docetaxel and Capecitabine For First Line Treatment of Her2-Positive Advanced Gastric Cancer
NCT02004769 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of DCC-2618 (Ripretinib) In Patients With With Advanced Gastrointestinal Stromal Tumors (GIST)
NCT04282980 ·Status: COMPLETED ·Phase: PHASE2
-
Cytoreductive Surgery Combined With HIPEC and Chemotherapy for Gastric Cancer With Peritoneal Metastasis
NCT03023436 ·Status: UNKNOWN ·Phase: PHASE3
-
A Phase Ib/2 Clinical Study of Fruquintinib Combined With Paclitaxel in the Treatment of Advanced Gastric Cancer
NCT02415023 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Single-center, Multi-cohort Exploratory Phase Ib/II Clinical Study of First-line Treatment of Unresectable Locally Advanced/Advanced Adenocarcinoma of the Stomach or Gastroesophageal Junction Based on Different Genotypes
NCT05608785 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Dose-dense Biweekly Docetaxel, Oxaliplatin and 5-fluorouracil as First-line Treatment in Advanced Gastric Cancer
NCT02289378 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase II Study of Albumin Bound Paclitaxel With 5-FU and CF as Second Line in Taxanes Naive Advanced Gastric Cancer
NCT02229045 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of CS3007 in Subjects With Gastrointestinal Stromal Tumor
NCT04254939 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Nonintervention Study on Peritoneal Metastasis of Stage IV Gastric Cancer
NCT03237507 ·Status: UNKNOWN