Mechanisms of Resistance to PSMA Radioligand Therapy
NCT05435495 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 125
Last updated 2026-03-18
Summary
This is a multicenter, correlative study to existing Lutetium based prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) trials and uses.
Conditions
Interventions
- PROCEDURE
-
Single-photon emission computed tomography
Imaging procedure
- PROCEDURE
-
Blood Draw
Blood draw for future research tests (45-60 mL).
- PROCEDURE
-
Tumor Biopsy
Guided biopsy of lesion
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Prostate Cancer Foundation
collaborator OTHER -
University of California, San Francisco
lead OTHER
Principal Investigators
-
Thomas Hope, MD · University of California, San Francisco
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-10-21
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- United States
Study Locations
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