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Assessment the Cancer Risk of Indeterminate Thyroid Nodules Through Integration of Clinical, Ultrasonographic and Multiomic Features

NCT05428371 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 256

Last updated 2022-06-23

No results posted yet for this study

Summary

Indeterminate thyroid nodules have a mild risk of malignancy (15-30%). The aim of our study is to individuate new biomarkers of thyroid carcinoma through multiomic analyses of blood samples and of specimen samples of patients with indeterminate thyroid nodules.

Conditions

Interventions

DIAGNOSTIC_TEST

Multiomic analyses of blood and surgical specimens

The following items will be evaluated: * cell free dna length and integrity * presence or absence of SNPs in cfDNA and in DNA extracted from surgical samples * qualitative and quantitative evaluation of serum and surgical specimens proteome (proteomics)

Sponsors & Collaborators

  • Prof. Pietro Giorgio Calò

    collaborator UNKNOWN

  • Dott. Gian Luigi Canu

    collaborator UNKNOWN

  • University of Cagliari

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-01
Primary Completion
2027-05-31
Completion
2027-12-31

Countries

  • Italy

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05428371 on ClinicalTrials.gov