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Rebreathing-induced Hypoxia and Glucose Levels

NCT05422430 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2026-05-06

No results posted yet for this study

Summary

The aim of this research project is to determine the effect of repeated maximal voluntary apneas on glucose uptake during an oral glucose tolerance test in healthy individuals, individuals with prediabetes and patients with type 2 diabetes.

Conditions

  • Hypoxemia

Interventions

BEHAVIORAL

Rebreathing-induced hypoxia

Participants will rebreathe room air from a low-volume closed-circuit system for a period of 2 minutes.

BEHAVIORAL

Spontaneous breathing

Participants will be spontaneously breathing during an oral glucose tolerance test.

Sponsors & Collaborators

  • University of Texas at Austin

    lead OTHER

Principal Investigators

  • Sophie Lalande · UT Austin

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-10-21
Primary Completion
2023-09-04
Completion
2025-10-13

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05422430 on ClinicalTrials.gov