MedTrace Logo

Evaluation of the Feasibility and Safety of Laryngoscopic Microsurgery Under Non-intubation Anesthesia

NCT05420649 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 49

Last updated 2023-10-27

No results posted yet for this study

Summary

Nonintubated anesthesia applied in combination with high-flow nasal oxygen (HFNO) is an alternative strategy for laryngeal microsurgery (LMS). LMS is a common procedure in otolaryngology that typically requires endotracheal tube intubation under general anesthesia. Endotracheal tube intubation causes complications; a nonintubated strategy can avoid these complications and provide a clearer surgical field of vision, enabling vocal cord inspection and disposal. Administering a muscle relaxant can also help prevent bucking during surgery but can engender apnea and hypercapnia, which may have negative effects on hemodynamics. Therefore, the investigators assessed the effectiveness of a superior laryngeal nerve block (SLNB) with intravenous general anesthesia in maintaining spontaneous breathing and improving safety during LMS with nonintubated anesthesia.

Conditions

  • Spontaneous Breathing
  • Laryngomicrosurgery
  • Superior Laryngeal Nerve Block

Interventions

PROCEDURE

Non-intubated Laryngomicrosurgery

Non-intubated LMS was performed with assistance of Optiflow (HFNO).

Sponsors & Collaborators

  • Kaohsiung Veterans General Hospital.

    lead OTHER

Principal Investigators

  • Yuan Yi Chia, Director · Kaohsiung Veterans General Hospital.

  • Yu Ting Kuo, physician · Kaohsiung Veterans General Hospital.

  • Ting Shou Chang, physician · Kaohsiung Veterans General Hospital.

  • Chih Chi Tsai, RA · Kaohsiung Veterans General Hospital.

  • Li-Ya Tseng, physician · Kaohsiung Veterans General Hospital.

  • Pei-Wen Shen, physician · Kaohsiung Veterans General Hospital.

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-20
Primary Completion
2022-10-26
Completion
2022-10-26

Countries

  • Taiwan

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05420649 on ClinicalTrials.gov