Clinical Trial of Reconstruction After Proximal Gastrectomy

Summary

1\) To explore a simple, safe, post-proximal gastrectomy reconstruction method with good absorption and digestive function in order to improve patients' postoperative quality of life; 2) To fill the gap in the comparison of clinical efficacy between left-open single-flap technique and double-flap technique in this specialized field in China; 3) To utilize the experience and foundation of gastrointestinal surgery in the treatment of gastric cancer and integrate the advantageous resources in China; 4) To establish a large-sample, multicenter randomized clinical study in order to promote the establishment and improvement of relevant norms of gastrointestinal reconstruction

Conditions

• Esophagitis, Reflux

Interventions

PROCEDURE

left-opening single-flap technique

left-opening single-flap technique

PROCEDURE

double-flap group technique

double-flap group technique

Sponsors & Collaborators

• Tang-Du Hospital

  collaborator OTHER

• First Affiliated Hospital Xi'an Jiaotong University

  collaborator OTHER

• General Hospital of Ningxia Medical University

  collaborator OTHER

• Henan Provincial People's Hospital

  collaborator OTHER

• The First Affiliated Hospital of Shanxi Medical University

  collaborator OTHER

• Oncogastroenterology Committee of Chinese

  lead OTHER

Principal Investigators

• Nan Wang, MD · Tang-Du Hospital

• Chao Zhang, MD · Henan Provincial People's Hospital

• Lei Wang, MD · General Hospital of Ningxia Medical University

• Renwei Chang, MD · The First Affiliated Hospital of Shanxi Medical University

• Junjun She, MD · First Affiliated Hospital Xi'an Jiaotong University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-08-01

Primary Completion

2024-07-31

Completion

2027-07-31