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DESCARTES: De-ESCAlation of RadioTherapy in Patients With Pathologic Complete rESponse to Neoadjuvant Systemic Therapy

NCT05416164 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 595

Last updated 2025-03-26

No results posted yet for this study

Summary

This study evaluates whether radiotherapy can safely be omitted in breast cancer patients with T1-2N0 tumors who achieve a pathologic complete response after neoadjuvant systemic therapy and breast-conserving surgery

Conditions

Interventions

RADIATION

Omission of radiotherapy

Omission of radiotherapy

Sponsors & Collaborators

  • Dutch Cancer Society

    collaborator OTHER

  • Borstkanker Onderzoek Groep

    collaborator NETWORK

  • The Netherlands Cancer Institute

    lead OTHER

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-07
Primary Completion
2032-05-31
Completion
2037-05-31

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05416164 on ClinicalTrials.gov